This composite of three images shows the poterior lateral mechanosensory neuron (PLM) of C. elegans, with the cytoplasm visualized with a red fluorophore and the fusogen EFF-1 tagged with GFP. Mutations in rab-5 cause vesicles to emanate from the PLM neuron. These are visible as puncta surrounding the cell body and initial section of the PLM axon. Photo by Casey Linton and Nick Valmas. For more information see the article by Linton et al. (pages 2823–2836).