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Research Articles, Behavioral/Cognitive

MDMA Increases Cooperation and Recruitment of Social Brain Areas When Playing Trustworthy Players in an Iterated Prisoner's Dilemma

Anthony S. Gabay, Matthew J. Kempton, James Gilleen and Mitul A. Mehta
Journal of Neuroscience 9 January 2019, 39 (2) 307-320; DOI: https://doi.org/10.1523/JNEUROSCI.1276-18.2018
Anthony S. Gabay
1Department of Neuroimaging,
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Matthew J. Kempton
1Department of Neuroimaging,
2Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, United Kingdom, and
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James Gilleen
2Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, United Kingdom, and
3Department of Psychology, University of Roehampton, London SW15 5PJ, United Kingdom
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Mitul A. Mehta
1Department of Neuroimaging,
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1276-18.2018
PubMed 
30455187
Published By 
Society for Neuroscience
History 
  • Received May 22, 2018
  • Revision received October 19, 2018
  • Accepted October 23, 2018
  • First published November 19, 2018.
  • Version of record published January 9, 2019.
Copyright & Usage 
Copyright © 2019 the authors 0270-6474/19/390308-14$15.00/0

Author Information

  1. Anthony S. Gabay1,
  2. Matthew J. Kempton1,2,
  3. James Gilleen2,3,*, and
  4. Mitul A. Mehta1,*
  1. 1Department of Neuroimaging,
  2. 2Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, United Kingdom, and
  3. 3Department of Psychology, University of Roehampton, London SW15 5PJ, United Kingdom
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Author contributions

  1. Author contributions: A.S.G. wrote the first draft of the paper; A.S.G., M.J.K., J.G., and M.A.M. edited the paper; A.S.G., M.J.K., J.G., and M.A.M. designed research; A.S.G. performed research; A.S.G. analyzed data; A.S.G. and M.A.M. wrote the paper.

  2. ↵*J.G. and M.A.M. contributed equally to this work.

Disclosures

    • Received May 22, 2018.
    • Revision received October 19, 2018.
    • Accepted October 23, 2018.
  • A.S.G. was supported by an IoPPN-MRC Excellence award. M.J.K. was supported by Medical Research Council Fellowship Grant MR/J008915/1. M.A.M. and M.J.K. were supported by the National Institute for Health Research Biomedical Research Centre at South London and the Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the National Institute for Health Research, or the Department of Health and Social Care. J.G. was supported by the British Academy. We thank the study participants for time and commitment to the study; Dr. Ottavia Dipasquale for assistance with the receptor density analysis; and South London & Maudsley NHS Trust Pharmacy for managing the supply and access to MDMA.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Anthony S. Gabay, Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology & Neuroscience (089), De Crespigny Park, London SE5 8AF, UK. anthony.a.gabay{at}kcl.ac.uk

Other Version

  • previous version (November 19, 2018).
  • You are viewing the most recent version of this article.

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Article usage: November 2018 to February 2023

AbstractFullPdf
Nov 201846250146
Dec 20181572055
Total 201861970201
Jan 20191983225107
Feb 20196986235
Mar 20197164527
Apr 20196115525
May 20195592725
Jun 201914122718
Jul 20198514321
Aug 20194622227
Oct 20197737264
Nov 201957304242
Dec 20193319940
Total 201962771681631
Jan 20203224135
Feb 20203726771
Mar 20203822040
May 20204723744
Jun 20208919441
Jul 20201324632
Aug 20201716918
Sep 20202913946
Oct 20205919863
Nov 20203822753
Dec 20203117629
Total 20204302314472
Jan 20214121635
Feb 20214821455
Mar 20214020636
Apr 20214422671
May 20212420639
Jun 20211513522
Jul 20212912845
Aug 20211535635
Sep 20212917540
Oct 20213922052
Nov 20212615936
Dec 20211414836
Total 20213642389502
Jan 20225016950
Feb 20224017249
Mar 20226320942
Apr 20225025460
May 20222918823
Jun 20221813340
Jul 20222915345
Aug 20222912032
Sep 20225213144
Oct 20224726933
Nov 202273219
Dec 202212459
Total 20224261875446
Jan 20236315835
Feb 20232161
Total 20236517436
Total1375984332288
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The Journal of Neuroscience: 39 (2)
Journal of Neuroscience
Vol. 39, Issue 2
9 Jan 2019
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MDMA Increases Cooperation and Recruitment of Social Brain Areas When Playing Trustworthy Players in an Iterated Prisoner's Dilemma
Anthony S. Gabay, Matthew J. Kempton, James Gilleen, Mitul A. Mehta
Journal of Neuroscience 9 January 2019, 39 (2) 307-320; DOI: 10.1523/JNEUROSCI.1276-18.2018

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MDMA Increases Cooperation and Recruitment of Social Brain Areas When Playing Trustworthy Players in an Iterated Prisoner's Dilemma
Anthony S. Gabay, Matthew J. Kempton, James Gilleen, Mitul A. Mehta
Journal of Neuroscience 9 January 2019, 39 (2) 307-320; DOI: 10.1523/JNEUROSCI.1276-18.2018
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Keywords

  • fMRI
  • MDMA
  • Prisoner's Dilemma
  • psychopharmacology
  • social cognition
  • social decision-making

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