This Week in The Journal

A D₂ receptor agonist (applied during the time indicated by blue bar) increases the activity of striatal cholinergic interneurons in mice with dystonia-linked mutations in THAP1 (red, top) or GNAL (red, bottom), but not in wild-type mice (black, both panels). See Jaunarajs, Scarduzio, et al. for details.