The Cofilin/Limk1 Pathway Controls the Growth Rate of Both Developing and Regenerating Motor Axons

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¹Department of Neurobiology,
²Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, California 90095, and
³Neuroscience Graduate Program, Department of Biological Sciences, University of Southern California, Los Angeles, California 90089

Author contributions: M.E.F., A.d.S., K.D.P., and S.J.B. designed research; M.E.F., A.d.S., K.D.P., S.R., and S.J.B. performed research; M.E.F., A.d.S., K.D.P., S.R., and S.J.B. analyzed data; M.E.F., A.d.S., K.D.P., and S.J.B. edited the paper; S.J.B. wrote the paper.

This work was supported by National Institutes of Health National Research Service Award Fellowship NS 077619 to M.E.F., and Craig H. Neilsen Foundation Grant 284402, Merkin Foundation, and National Institutes of Health Grant NS 063999 to S.J.B. We thank Zhengping Zia for the Limk1 mutant mice line; Bennett Novitch for FoxP1 antibodies; Aaron McGee for teaching us the sciatic crush protocol; David McKemy and his laboratory for help with the sensory behavioral tests; Tanmoy Bhattacharya, Olivia Handley, Harley Kornblum, Francesca Mariani, Aaron McGee, Bennett Novitch, Caroline Pearson, and Larry Zipursky for invaluable discussions; and Reggie Edgerton, Bennett Novitch, and Larry Zipursky for comments on the manuscript.
The authors declare no competing financial interests.
Correspondence should be addressed to Samantha J. Butler at butlersj{at}ucla.edu

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