This image shows a section from a mouse dorsal root ganglion stained for Interferon Alpha and Beta Receptor Subunit 1 (mRNA; red) along with the sensory neuron markers calcitonin gene-related peptide (mRNA; green), purinergic receptor P2X3 (mRNA; blue) and Neurofilament-200 (protein; cyan). Interferon receptors were robustly expressed in sensory neurons in the dorsal root ganglion and their activation produces pain via an eIF4E-dependent translation mechanism. For more information, see the article Barragán-Iglesias, et al. 2020. (pages 3517–3532).