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Research Articles, Cellular/Molecular

Disruption of tmc1/2a/2b Genes in Zebrafish Reveals Subunit Requirements in Subtypes of Inner Ear Hair Cells

Eliot T. Smith, Itallia Pacentine, Anna Shipman, Matthew Hill and Teresa Nicolson
Journal of Neuroscience 3 June 2020, 40 (23) 4457-4468; DOI: https://doi.org/10.1523/JNEUROSCI.0163-20.2020
Eliot T. Smith
1Department of Otolaryngology Head and Neck Surgery, Stanford School of Medicine, Stanford University, Stanford, California 94305
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Itallia Pacentine
2Oregon Hearing Research Center, Oregon Health and Science University, Portland, Oregon 97239
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  • ORCID record for Itallia Pacentine
Anna Shipman
1Department of Otolaryngology Head and Neck Surgery, Stanford School of Medicine, Stanford University, Stanford, California 94305
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Matthew Hill
2Oregon Hearing Research Center, Oregon Health and Science University, Portland, Oregon 97239
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Teresa Nicolson
1Department of Otolaryngology Head and Neck Surgery, Stanford School of Medicine, Stanford University, Stanford, California 94305
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0163-20.2020
PubMed 
32371604
Published By 
Society for Neuroscience
History 
  • Received January 15, 2020
  • Revision received April 14, 2020
  • Accepted April 16, 2020
  • First published May 5, 2020.
  • Version of record published June 3, 2020.
Copyright & Usage 
Copyright © 2020 the authors

Author Information

  1. Eliot T. Smith1,
  2. Itallia Pacentine2,
  3. Anna Shipman1,
  4. Matthew Hill2, and
  5. Teresa Nicolson1
  1. 1Department of Otolaryngology Head and Neck Surgery, Stanford School of Medicine, Stanford University, Stanford, California 94305
  2. 2Oregon Hearing Research Center, Oregon Health and Science University, Portland, Oregon 97239
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Author contributions

  1. Author contributions: E.T.S., I.P., and T.N. designed research; E.T.S., I.P., A.S., and M.H. performed research; E.T.S., I.P., A.S., M.H., and T.N. analyzed data; E.T.S. wrote the first draft of the paper; E.T.S., I.P., A.S., andT.N. edited the paper; E.T.S. wrote the paper.

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Disclosures

    • Received January 15, 2020.
    • Revision received April 14, 2020.
    • Accepted April 16, 2020.
  • This work was supported by National Institute on Deafness and Other Communication Disorders R01 DC013572 and DC013531 to T.N.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Teresa Nicolson at tnicolso{at}stanford.edu

Other Version

  • previous version (May 05, 2020).
  • You are viewing the most recent version of this article.

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May 2020873079
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Jul 20202052917
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Apr 202275719
Total 20225020175
Total29341047672
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The Journal of Neuroscience: 40 (23)
Journal of Neuroscience
Vol. 40, Issue 23
3 Jun 2020
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Disruption of tmc1/2a/2b Genes in Zebrafish Reveals Subunit Requirements in Subtypes of Inner Ear Hair Cells
Eliot T. Smith, Itallia Pacentine, Anna Shipman, Matthew Hill, Teresa Nicolson
Journal of Neuroscience 3 June 2020, 40 (23) 4457-4468; DOI: 10.1523/JNEUROSCI.0163-20.2020

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Disruption of tmc1/2a/2b Genes in Zebrafish Reveals Subunit Requirements in Subtypes of Inner Ear Hair Cells
Eliot T. Smith, Itallia Pacentine, Anna Shipman, Matthew Hill, Teresa Nicolson
Journal of Neuroscience 3 June 2020, 40 (23) 4457-4468; DOI: 10.1523/JNEUROSCI.0163-20.2020
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Keywords

  • auditory/vestibular system
  • hair cells
  • inner ear
  • mechanoelectrical transduction
  • mechanosensation
  • TMC proteins

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