This image shows a parvalbuminexpressing inhibitory basket cell (green) in the hippocampus of an amyloid-depositing 5xFAD mouse. The cell has been morphologically reconstructed after patch clamp recording of spontaneous synaptic activity during sharp wave ripple events. Non-patched parvalbumin neurons are labeled in red. For more information, see the article by Caccavano et al. (pages 5116–5136).