This image shows corticofugal axons (green) projecting from layer 5 of the mouse primary visual cortex to the dorsal striatum. Layer 5 projections from primary visual, primary somatosensory, primary motor, and ventromedial orbitofrontal cortex all have terminal fields within the striatum, among other common targets. Blue is DAPi nuclear stain. For more information, see the article by Prasad et al. (pages 5785–5796).