Article Information
- Received May 2, 2019
- Revision received October 21, 2019
- Accepted October 23, 2019
- First published December 4, 2019.
- Version of record published January 22, 2020.
Author Information
- 1F.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115,
- 2Departments of Biology and Neurobiology, and Bio-X, James H. Clark Center, Stanford University, Stanford, California 94305,
- 3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, and
- 4Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts 02115
Author contributions
Author contributions: C.A.W., C.-É.S., and B.S. designed research; C.A.W. and C.-É.S. performed research; R.W.S. contributed unpublished reagents/analytic tools; C.A.W. and C.-É.S. analyzed data; C.A.W. wrote the paper.
Disclosures
- Received May 2, 2019.
- Revision received October 21, 2019.
- Accepted October 23, 2019.
This work was supported by the National Institute of Neurological Disorders and Stroke (NINDS; R01-NS-071008). We thank Daniel Tom, Ryan Carelli, Michael Blanchard, and Michelle Ocana of the Neurobiology Imaging Facility at Harvard Medical School (NINDS P30 Core Center Grant NS072030); Cassandra-Victoria Innocent of the Intellectual and Developmental Disabilities Research Center (IDDRC) Cellular Imaging Core at Boston Children's Hospital (U54 HD090255) for help with imaging; Allie Muthukumar for technical help with SIM imaging; the Harvard Center for Biological Imaging for infrastructure and support; Nick Andrews of the Neurodevelopmental Behavioral Core at Boston Children's Hospital (CHB IDDRC, 1U54HD090255) for providing a dark room; Carla Shatz for scientific advice and for generously sharing a mouse Arc probe; Tim Hammond and Chinfei Chen for critical reading of the paper; and Dorathy Vargas for help with mouse colony maintenance. We also acknowledge NIH SIG award (1S10RR029237-01), which was used to acquire the ELYRA microscope at the Harvard Center for Biological Imaging.
B.S. serves on the scientific advisory board of Annexon and is a minor shareholder of Annexon. The remaining authors declare no competing financial interests.
- Correspondence should be addressed to Beth Stevens at beth.stevens{at}childrens.harvard.edu
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