Article Information
- Received April 23, 2020
- Revision received August 18, 2020
- Accepted September 1, 2020
- First published October 12, 2020.
- Version of record published November 4, 2020.
Author Information
- Taiji Tsunemi1,2,
- Yuta Ishiguro2,
- Asako Yoroisaka2,
- Clarissa Valdez3,
- Kengo Miyamoto2,
- Keiichi Ishikawa3,
- Shinji Saiki2,
- Wado Akamatsu3,
- Nobutaka Hattori2, and
- Dimitri Krainc1
- 1Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611
- 2Department of Neurology, School of Medicine, Juntendo University, Tokyo 113-8421, Japan
- 3Center for Genomic and Regenerative Medicine, School of Medicine, Juntendo University, Tokyo 113-8421, Japan
Author contributions
Author contributions: T.T., W.A., and D.K. designed research; T.T., Y.I., A.Y., C.V., K.M., and K.I. performed research; S.S. contributed unpublished reagents/analytic tools; T.T., W.A., and D.K. analyzed data; T.T., N.H., and D.K. wrote the paper.
Disclosures
- Received April 23, 2020.
- Revision received August 18, 2020.
- Accepted September 1, 2020.
D.K. is the Founder and Scientific Advisory Board Chair of Lysosomal Therapeutics Inc. and Vanqua Bio; serves on the scientific advisory boards of The Silverstein Foundation, Intellia Therapeutics, and Prevail Therapeutics; and is a Venture Partner at OrbiMed. The authors declare no other competing financial interests.
This work is supported by National Institutes of Health Grant R37-NS-096241 (to D.K.); Japan Society for the Promotion of Science KAKENHI Grant 18K07510 and Juntendo University Research Institute for Environmental and Gender-Specific Medicine (to T.T.); Strategic Research Foundation Grant-in-Aid for Private Universities (to T.T., Y.I., K.I., S.S., W.A., and N.H.); and the Rare/Intractable Disease Project of the Japan from AMED Grants JP17ek0109244 and JP20ek0109429 (to T.T., K.I., S.S., W.A., and N.H.).
- Correspondence should be addressed to Dimitri Krainc at dkrainc{at}nm.org or Taiji Tsunemi at t-tsunemi{at}juntendo.ac.jp
Funding
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)
R37 NS096241Japan Society for the Promotion of Science (JSPS)
18K07510Strategic Research Foundation Grant-in-Aid for Private Universities
The Rare/Intractable Disease Project of the Japan from AMED
JP17ek0109244; JP20ek0109429
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