This image shows neurolucida reconstructions of layer 5 pyramidal neurons in the anterior cingulate cortex. The apical dendrite of these cells is characterized by efficient low-pass dendrosomatic coupling which may allow them to achieve efficient integration of subthreshold distal synaptic inputs. For more information, see the article by Marti Mengual, Wybo et al. (pages 8799–8815). Cover image: Natalie Elisabeth Nevian (University of Bern, Bern, Switzerland).