Article Information
- Received August 1, 2019
- Revision received December 8, 2019
- Accepted December 23, 2019
- First published January 24, 2020.
- Version of record published February 26, 2020.
Author Information
- William J. Meilandt1,
- Hai Ngu2,
- Alvin Gogineni3,
- Guita Lalehzadeh1,
- Seung-Hye Lee1,
- Karpagam Srinivasan1,
- Jose Imperio1,
- Tiffany Wu1,
- Martin Weber1,
- Agatha J. Kruse3,
- Kimberly L. Stark1,
- Pamela Chan5,
- Mandy Kwong5,
- Zora Modrusan6,
- Brad A. Friedman4,
- Justin Elstrott3,
- Oded Foreman2,
- Amy Easton1,
- Morgan Sheng1, and
- David V. Hansen1
Author contributions
Author contributions: W.J.M., K.L.S., J.E., A.E., M.S., and D.V.H. designed research; W.J.M., A.G., G.L., S.-H.L., K.S., J.I., T.W., M.W., A.J.K., P.C., M.K., and Z.M. performed research; W.J.M., H.N., A.G., S.-H.L., P.C., B.A.F., O.F., and D.V.H. analyzed data; W.J.M., H.N., M.W., A.E., M.S., and D.V.H. edited the paper; W.J.M. and D.V.H. wrote the paper; H.N. contributed unpublished reagents/analytic tools; D.V.H. wrote the first draft of the paper.
Disclosures
- Received August 1, 2019.
- Revision received December 8, 2019.
- Accepted December 23, 2019.
We thank Melissa Gonzales Edick and Joanna Yung for imaging support; members of the Genentech animal care staff, FACS laboratory, and RNA sequencing laboratory for other research support; and Chris Bohlen for helpful critique of the manuscript.
All authors are or were employees of Genentech, Inc., with interests in developing novel therapeutics for neurodegenerative diseases at the time of performing work for this manuscript.
- Correspondence should be addressed to David V. Hansen at hansen.david{at}gene.com or William J. Meilandt at meilandt.william{at}gene.com
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