Article Information
- Received November 10, 2020
- Revision received January 23, 2021
- Accepted March 2, 2021
- First published April 12, 2021.
- Version of record published May 19, 2021.
Author Information
- Margaret L. Westwater1,2,
- Flavia Mancini3,
- Adam X. Gorka2,
- Jane Shapleske4,
- Jaco Serfontein4,
- Christian Grillon2,
- Monique Ernst2,
- Hisham Ziauddeen1,5,*, and
- Paul C. Fletcher1,5,*
- 1Department of Psychiatry, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0SZ, United Kingdom
- 2National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892
- 3Computational and Biological Learning Laboratory, Department of Engineering, University of Cambridge, Cambridge CB2 1PZ, United Kingdom
- 4Adult Eating Disorders Service, Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge CB21 5EF, United Kingdom
- 5Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, United Kingdom
Author contributions
Author contributions: M.L.W., F.M., J. Shapleske, J. Serfontein, H.Z., and P.C.F. designed research; M.L.W. and H.Z. performed research; M.L.W., F.M., A.X.G., C.G., M.E., and P.C.F. contributed unpublished reagents/analytic tools; M.L.W. analyzed data; M.L.W. wrote the paper.
↵*H.Z. and P.C.F. jointly supervised this research.
Disclosures
- Received November 10, 2020.
- Revision received January 23, 2021.
- Accepted March 2, 2021.
Funding was provided by the Bernard Wolfe Health Neuroscience Fund to P.C.F. and H.Z. and a Wellcome Trust Investigator Award to P.C.F. (Reference No. 206368/Z/17/Z). M.L.W. was supported through the National Institutes of Health-Oxford-Cambridge Scholars Program and a Cambridge Trust fellowship. F.M. was supported by research grants from Versus Arthritis, the Experimental Psychological Society, and a Career Development Award from the Medical Research Council (MR/T010614/1). A.X.G., C.G., and M.E. were supported by the Intramural Research Program of the National Institute of Mental Health (reference #ZIAMH002798). We thank the Wellcome Trust/National Institute for Health Research Clinical and Translational Research Facilities, and the Wolfson Brain Imaging Center for providing equipment and support staff for the study. We also thank the participants for time and dedication to this project; the nursing staff and radiographers for assisting the study protocol; and Dr. Bram Zandbelt for sharing the Stop-signal anticipation task code. In addition, we thank the Beat Eating Disorders charity for advertising the study.
The authors declare no competing financial interests.
- Correspondence should be addressed to Margaret L. Westwater at mw658{at}cam.ac.uk
Funding
Wellcome Trust (Wellcome)
206368/Z/17/ZBernard Wolfe Health Neuroscience Fund
Medical Research Council Career Development Award
MR/T010614/1Versus Arthritis
Experimental Psychological Society
Intramural Research Program of the NIMH
ZIAMH002798; ZIAMH002798NIH-Oxford Cambridge Scholars Program
Cambridge Trust
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