Article Information
- Received December 7, 2020
- Revision received April 7, 2021
- Accepted April 8, 2021
- First published April 29, 2021.
- Version of record published June 9, 2021.
Author Information
Author contributions
Author contributions: G.C., F.N., K.Z.P., J.A.-S., E.M.S.S., and J.E.M. designed research; G.C., F.N., K.Z.P., E.M.S.S., and J.E.M. performed research; G.C., F.N., K.Z.P., J.A.-S., E.M.S.S., and J.E.M. analyzed data; G.C., K.Z.P., J.A.-S., and E.M.S.S. edited the paper; F.N. wrote the paper; J.E.M. wrote the first draft of the paper.
↵*G.C. and F.N. contributed equally to this work.
Disclosures
- Received December 7, 2020.
- Revision received April 7, 2021.
- Accepted April 8, 2021.
This work was supported by Biotechnology and Biological Sciences Research Council Grant BB/M007391/1 to J.E.M., European Commission Grant GA 631404 to J.E.M., Leverhulme Trust Grant RPG-2017-417 to J.E.M. and J.A.-S., and Tromsø Research Foundation Grant 19-SG-JMcC to J.E.M. We thank the staff of the Division of Biomedical Services, Preclinical Research Facility, University of Leicester, for technical support and care of experimental animals; Heramb Chadchankar and Michelle Murphy for preliminary work; Vaibhav Konanur for developing the analytical method used to correct fluorescence traces; Leon Lagnado for kindly loaning equipment used in initial photometry experiments; and Andrew MacAskill for useful discussions regarding analysis.
The authors declare no competing financial interests.
- Correspondence should be addressed to James Edgar McCutcheon at j.mccutcheon{at}uit.no
Funding
Biotechnology and Biological Sciences Research Council (BBSRC)
BB/M007391/1European Commission (EC)
GA 631404Leverhulme Trust
RPG-2017-417Tromsø Research Foundation
19-SG-JMcC
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