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Research Articles, Systems/Circuits

Accounting for Biases in the Estimation of Neuronal Signal Correlation

Dean A. Pospisil and Wyeth Bair
Journal of Neuroscience 30 June 2021, 41 (26) 5638-5651; https://doi.org/10.1523/JNEUROSCI.2775-20.2021
Dean A. Pospisil
1Department of Biological Structure, Washington National Primate Research Center, University of Washington, Seattle, Washington 98195
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Wyeth Bair
1Department of Biological Structure, Washington National Primate Research Center, University of Washington, Seattle, Washington 98195
2Institute for Neuroengineering, University of Washington, Seattle, Washington 98194
3Computational Neuroscience Center, University of Washington, Seattle, Washington 98194
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2775-20.2021
PubMed 
34001625
Published By 
Society for Neuroscience
History 
  • Received October 12, 2020
  • Revision received February 10, 2021
  • Accepted May 2, 2021
  • First published May 17, 2021.
  • Version of record published June 30, 2021.
Copyright & Usage 
Copyright © 2021 the authors SfN exclusive license.

Author Information

  1. Dean A. Pospisil1 and
  2. Wyeth Bair1,2,3
  1. 1Department of Biological Structure, Washington National Primate Research Center, University of Washington, Seattle, Washington 98195
  2. 2Institute for Neuroengineering, University of Washington, Seattle, Washington 98194
  3. 3Computational Neuroscience Center, University of Washington, Seattle, Washington 98194
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Author contributions

  1. Author contributions: D.A.P. and W.B. designed research; D.A.P. performed research; D.A.P. analyzed data; D.A.P. wrote the first draft of the paper; D.A.P. and W.B. edited the paper; D.A.P. and W.B. wrote the paper.

Disclosures

    • Received October 12, 2020.
    • Revision received February 10, 2021.
    • Accepted May 2, 2021.
  • This work was supported by a National Science Foundation Graduate Research Fellowship DGE-1256082 (D.A.P.), National Institutes of Health Grant NEI R01-EY02999, and National Institutes of Health Grant NEI R01-EY027023 (W.B.). We thank Adam Kohn for reading and providing comments on the manuscript. We thank Ehud Zohary and William T. Newsome for sharing data and making it publicly available. We thank Greg Horwitz, Anitha Pasupathy, and Matthew Farrell for helpful discussions.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dean A. Pospisil at deanp3{at}uw.edu

Funding

  • HHS | NIH | National Eye Institute (NEI)

    NIH/NEI R01-EY027023; NIH/NEI R01-EY029997
  • National Science Foundation (NSF)

    DGE-1256082

Other Version

  • previous version (May 17, 2021).
  • You are viewing the most recent version of this article.

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May 2021373023
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Total23022551647
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The Journal of Neuroscience: 41 (26)
Journal of Neuroscience
Vol. 41, Issue 26
30 Jun 2021
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Accounting for Biases in the Estimation of Neuronal Signal Correlation
Dean A. Pospisil, Wyeth Bair
Journal of Neuroscience 30 June 2021, 41 (26) 5638-5651; DOI: 10.1523/JNEUROSCI.2775-20.2021

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Accounting for Biases in the Estimation of Neuronal Signal Correlation
Dean A. Pospisil, Wyeth Bair
Journal of Neuroscience 30 June 2021, 41 (26) 5638-5651; DOI: 10.1523/JNEUROSCI.2775-20.2021
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Keywords

  • confound
  • correlation
  • dimensionality
  • MT
  • statistics
  • variability

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