This pseudocolored confocal image shows a CA1 pyramidal neuron expressing GFP-tagged Trio. Prominent synaptic targeting of this glutamatergic synapse regulatory protein (in purple) can be seen in the apical and basal dendrites of the neuron. For more information, see the article by Tian and Paskus (pages 7768–7778). Cover image: Chen Tian and Jeremiah Paskus.