Global and Regional Damages in Retinal Ganglion Cell Axon Bundles Monitored Non-Invasively by Visible-Light Optical Coherence Tomography Fibergraphy

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¹Department of Biology, University of Virginia, Charlottesville, Virginia 22904
²Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208
³Department of Ophthalmology, University of Virginia, Charlottesville, Virginia 22904
⁴Program in Fundamental Neuroscience, University of Virginia, Charlottesville, Virginia 22904
⁵Department of Psychology, University of Virginia, Charlottesville, Virginia 22904

Author contributions: X.L., M.G., D.A.M., M.L., and H.F.Z. designed research; X.L., M.G., D.A.M., M.L., P.N., and H.F.Z. performed research; X.L., C.D.D., and H.F.Z. contributed unpublished reagents/analytic tools; X.L., M.G., D.A.M., M.L., P.N., P.A.N., and H.F.Z. analyzed data; X.L., M.G., and D.A.M. wrote the first draft of the paper; X.L., M.G., D.A.M., M.L., P.N., C.D.D., P.A.N., and H.F.Z. edited the paper; X.L., M.G., D.A.M., and H.F.Z. wrote the paper.
↵*M.G., D.A.M., and M.L. contributed equally to this work.

This work was supported in part by National Institutes of Health Grants R01EY026078, R01EY029121, R01EY028304, R01EY019949, R01EY026286, and R44EY026466. We thank Ashley Mason for her help with BAX mice breeding. We also thank Jingyi Gao, James Cole, and Prof. Ignacio Provencio for their fruitful discussions.
H.F.Z. has financial interests in Opticent Health, which did not support this work. All other authors declare no competing financial interests.
Correspondence should be addressed to Hao F. Zhang at hfzhang{at}northwestern.edu or Xiaorong Liu at xl8n{at}virginia.edu

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