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Symposium/Mini-Symposium

Patch-seq: Past, Present, and Future

Marcela Lipovsek, Cedric Bardy, Cathryn R. Cadwell, Kristen Hadley, Dmitry Kobak and Shreejoy J. Tripathy
Journal of Neuroscience 3 February 2021, 41 (5) 937-946; DOI: https://doi.org/10.1523/JNEUROSCI.1653-20.2020
Marcela Lipovsek
1Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE1 1UL, United Kingdom
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  • ORCID record for Marcela Lipovsek
Cedric Bardy
2Laboratory for Human Neurophysiology and Genetics, South Australian Health and Medical Research Institute (SAHMRI), Adelaide 5000, SA, Australia
3College of Medicine and Public Health, Flinders University, Bedford Park 5042, SA, Australia
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Cathryn R. Cadwell
4Department of Pathology, University of California San Francisco, San Francisco, California 94143
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Kristen Hadley
5Allen Institute for Brain Science, Seattle, Washington 98109
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Dmitry Kobak
6Institute for Ophthalmic Research, University of Tübingen, 72076 Tübingen, Germany
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Shreejoy J. Tripathy
7Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, Ontario M5T 1R8, Canada
8Department of Psychiatry, University of Toronto, Toronto, Ontario M5T 1R8, Canada
9Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1653-20.2020
PubMed 
33431632
Published By 
Society for Neuroscience
History 
  • Received June 30, 2020
  • Revision received November 11, 2020
  • Accepted October 22, 2020
  • First published January 11, 2021.
  • Version of record published February 3, 2021.
Copyright & Usage 
Copyright © 2021 the authors SfN exclusive license.

Author Information

  1. Marcela Lipovsek1,
  2. Cedric Bardy2,3,
  3. Cathryn R. Cadwell4,
  4. Kristen Hadley5,
  5. Dmitry Kobak6, and
  6. Shreejoy J. Tripathy7,8,9
  1. 1Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE1 1UL, United Kingdom
  2. 2Laboratory for Human Neurophysiology and Genetics, South Australian Health and Medical Research Institute (SAHMRI), Adelaide 5000, SA, Australia
  3. 3College of Medicine and Public Health, Flinders University, Bedford Park 5042, SA, Australia
  4. 4Department of Pathology, University of California San Francisco, San Francisco, California 94143
  5. 5Allen Institute for Brain Science, Seattle, Washington 98109
  6. 6Institute for Ophthalmic Research, University of Tübingen, 72076 Tübingen, Germany
  7. 7Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, Ontario M5T 1R8, Canada
  8. 8Department of Psychiatry, University of Toronto, Toronto, Ontario M5T 1R8, Canada
  9. 9Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada
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Author contributions

Disclosures

    • Received June 30, 2020.
    • Revision received November 11, 2020.
    • Accepted October 22, 2020.
  • The authors declare no competing financial interests.

  • M.L. was supported by a Consolidator Grant from the European Research Council (Grant 725729; FUNCOPLAN) to Matthew Grubb. C.B. was supported by the Ian Potter Foundation, the Flinders Foundation, Impact Philanthropy, Cancer Australia, and the Australian Department of Health. K.H. was supported by the Allen Institute for Brain Sciences. D.K. was supported by the Deutsche Forschungsgemeinschaft (Grant BE5601/4-1 and the Cluster of Excellence “Machine Learning—New Perspectives for Science”, EXC 2064, Project 390727645), the Federal Ministry of Education and Research (Grants FKZ 01GQ1601 and 01IS18039A), and the National Institute of Mental Health of the National Institutes of Health under Award Number U19MH114830. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. S.J.T. was supported by the CAMH Discovery Fund, the Krembil Foundation, the Kavli Foundation, the Canadian Institutes of Health Research (Grant NGN-171423), and the Natural Sciences and Engineering Research Council of Canada (Grants RGPIN-2020-05834 and DGECR-2020-00048). We thank Matthew Grubb for helpful comments on the manuscript and for kickstarting the organization of the mini-symposium.

  • Correspondence should be addressed to Marcela Lipovsek at marcela.lipovsek{at}kcl.ac.uk or Shreejoy J. Tripathy at shreejoy.tripathy{at}utoronto.ca

Funding

  • EC | European Research Council (ERC)

    725729; FUNCOPLAN (Awarded to Matthew Grubb)
  • Ian Potter Foundation (IPF)

  • Flinders Medical Centre Foundation (FMC Foundation)

  • Impact Philanthropy

  • Cancer Australia

  • Australian Department of Health

  • Allen Institute of Brain Sciences

  • Deutsche Forschungsgemeinschaft (DFG)

    BE5601/4-1; EXC 2064; project number 390727645
  • Federal Ministry of Education and Research

    FKZ 01GQ1601; 01IS18039A
  • HHS | NIH | National Institute of Mental Health (NIMH)

    U19MH114830
  • CAMH Discovery Fund

  • Krembil Foundation

  • Kavli Foundation

  • CIHR

    NGN-171423
  • Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC)

    RGPIN-2020-05834; DGECR-2020-00048

Other Version

  • previous version (January 11, 2021).
  • You are viewing the most recent version of this article.

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The Journal of Neuroscience: 41 (5)
Journal of Neuroscience
Vol. 41, Issue 5
3 Feb 2021
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Patch-seq: Past, Present, and Future
Marcela Lipovsek, Cedric Bardy, Cathryn R. Cadwell, Kristen Hadley, Dmitry Kobak, Shreejoy J. Tripathy
Journal of Neuroscience 3 February 2021, 41 (5) 937-946; DOI: 10.1523/JNEUROSCI.1653-20.2020

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Patch-seq: Past, Present, and Future
Marcela Lipovsek, Cedric Bardy, Cathryn R. Cadwell, Kristen Hadley, Dmitry Kobak, Shreejoy J. Tripathy
Journal of Neuroscience 3 February 2021, 41 (5) 937-946; DOI: 10.1523/JNEUROSCI.1653-20.2020
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Keywords

  • electrophysiology
  • transcriptomics
  • neuronal morphology
  • patch-clamp
  • single cell
  • multi-modal

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