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Research Articles, Behavioral/Cognitive

Opposing Roles of the Dorsolateral and Dorsomedial Striatum in the Acquisition of Skilled Action Sequencing in Rats

Karly M. Turner, Anna Svegborn, Mia Langguth, Colin McKenzie and Trevor W. Robbins
Journal of Neuroscience 9 March 2022, 42 (10) 2039-2051; DOI: https://doi.org/10.1523/JNEUROSCI.1907-21.2022
Karly M. Turner
1Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
2Behavioural and Cognitive Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
3School of Psychology, University of New South Wales, Sydney, New South Wales 2052, Australia
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Anna Svegborn
1Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
2Behavioural and Cognitive Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
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Mia Langguth
1Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
2Behavioural and Cognitive Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
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Colin McKenzie
1Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
2Behavioural and Cognitive Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
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Trevor W. Robbins
1Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
2Behavioural and Cognitive Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1907-21.2022
PubMed 
35086903
Published By 
Society for Neuroscience
History 
  • Received September 20, 2021
  • Revision received December 29, 2021
  • Accepted January 3, 2022
  • First published January 27, 2022.
  • Version of record published March 9, 2022.
Copyright & Usage 
Copyright © 2022 the authors SfN exclusive license.

Author Information

  1. Karly M. Turner1,2,3,
  2. Anna Svegborn1,2,
  3. Mia Langguth1,2,
  4. Colin McKenzie1,2, and
  5. Trevor W. Robbins1,2
  1. 1Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
  2. 2Behavioural and Cognitive Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
  3. 3School of Psychology, University of New South Wales, Sydney, New South Wales 2052, Australia
  • M. Langguth's present address: School of Psychology, University of Sydney, Sydney, New South Wales 2006, Australia.

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Author contributions

  1. Author contributions: K.M.T. and T.W.R. designed research; K.M.T., A.S., M.L., and C.M. performed research; K.M.T. analyzed data; K.M.T. wrote the first draft of the paper; K.M.T., A.S., M.L., C.M., and T.W.R. edited the paper; K.M.T. and T.W.R. wrote the paper.

  • M. Langguth's present address: School of Psychology, University of Sydney, Sydney, New South Wales 2006, Australia.

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Disclosures

    • Received September 20, 2021.
    • Revision received December 29, 2021.
    • Accepted January 3, 2022.
  • This work was supported by National Health and Medical Research Council Early Career Fellowship GNT1122221 to K.M.T. This work was supported in whole, or in part, by Wellcome Trust Grant 104631/Z/14/Z to T.W.R. For the purpose of open access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript version arising from this submission. Experiments were conducted under a Home Office Project License held by Dr. Amy Milton, and we thank her for supporting our research.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Karly M. Turner at karly.turner{at}unsw.edu.au

Funding

  • Department of Health | National Health and Medical Research Council (NHMRC)

    GNT1122221
  • Wellcome Trust (Wellcome)

    104631/Z/14/Z

Other Version

  • previous version (January 27, 2022).
  • You are viewing the most recent version of this article.

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The Journal of Neuroscience: 42 (10)
Journal of Neuroscience
Vol. 42, Issue 10
9 Mar 2022
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Opposing Roles of the Dorsolateral and Dorsomedial Striatum in the Acquisition of Skilled Action Sequencing in Rats
Karly M. Turner, Anna Svegborn, Mia Langguth, Colin McKenzie, Trevor W. Robbins
Journal of Neuroscience 9 March 2022, 42 (10) 2039-2051; DOI: 10.1523/JNEUROSCI.1907-21.2022

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Opposing Roles of the Dorsolateral and Dorsomedial Striatum in the Acquisition of Skilled Action Sequencing in Rats
Karly M. Turner, Anna Svegborn, Mia Langguth, Colin McKenzie, Trevor W. Robbins
Journal of Neuroscience 9 March 2022, 42 (10) 2039-2051; DOI: 10.1523/JNEUROSCI.1907-21.2022
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Keywords

  • automaticity
  • habit
  • orbitofrontal cortex
  • prefrontal cortex
  • skill
  • striatum

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