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Research Articles, Behavioral/Cognitive

Emotion Downregulation Targets Interoceptive Brain Regions While Emotion Upregulation Targets Other Affective Brain Regions

Jungwon Min, Kaoru Nashiro, Hyun Joo Yoo, Christine Cho, Padideh Nasseri, Shelby L. Bachman, Shai Porat, Julian F. Thayer, Catie Chang, Tae-Ho Lee and Mara Mather
Journal of Neuroscience 6 April 2022, 42 (14) 2973-2985; https://doi.org/10.1523/JNEUROSCI.1865-21.2022
Jungwon Min
1University of Southern California, Los Angeles, California 90089
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Kaoru Nashiro
1University of Southern California, Los Angeles, California 90089
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Hyun Joo Yoo
1University of Southern California, Los Angeles, California 90089
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Christine Cho
1University of Southern California, Los Angeles, California 90089
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Padideh Nasseri
1University of Southern California, Los Angeles, California 90089
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Shelby L. Bachman
1University of Southern California, Los Angeles, California 90089
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  • ORCID record for Shelby L. Bachman
Shai Porat
1University of Southern California, Los Angeles, California 90089
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Julian F. Thayer
2University of California, Irvine, California 92697
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Catie Chang
3Vanderbilt University, Nashville, Tennessee 37235
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Tae-Ho Lee
4Virginia Tech, Blacksburg, Virginia 24061
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Mara Mather
1University of Southern California, Los Angeles, California 90089
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1865-21.2022
PubMed 
35193926
Published By 
Society for Neuroscience
History 
  • Received September 14, 2021
  • Revision received January 6, 2022
  • Accepted January 31, 2022
  • First published February 22, 2022.
  • Version of record published April 6, 2022.
Copyright & Usage 
Copyright © 2022 the authors SfN exclusive license.

Author Information

  1. Jungwon Min1,
  2. Kaoru Nashiro1,
  3. Hyun Joo Yoo1,
  4. Christine Cho1,
  5. Padideh Nasseri1,
  6. Shelby L. Bachman1,
  7. Shai Porat1,
  8. Julian F. Thayer2,
  9. Catie Chang3,
  10. Tae-Ho Lee4, and
  11. Mara Mather1
  1. 1University of Southern California, Los Angeles, California 90089
  2. 2University of California, Irvine, California 92697
  3. 3Vanderbilt University, Nashville, Tennessee 37235
  4. 4Virginia Tech, Blacksburg, Virginia 24061
View Full Text

Author contributions

  1. Author contributions: J.M., K.N., H.J.Y., J.F.T., C. Chang, and M.M. designed research; J.M., K.N., H.J.Y., C. Cho, P.N., S.L.B., and S.P. performed research; J.M., K.N., and M.M. analyzed data; J.M. wrote the first draft of the paper; J.M., K.N., H.J.Y., C. Cho, P.N., S.L.B., S.P., J.F.T., C. Chang, T.L., and M.M. edited the paper; J.M. and M.M. wrote the paper; T.L. contributed unpublished reagents/analytic tools.

View Abstract

Disclosures

    • Received September 14, 2021.
    • Revision received January 6, 2022.
    • Accepted January 31, 2022.
  • This work was supported by National Institutes of Health R01AG057184 to M.M. We thank our research assistants for help with data collection: Linette Bagtas, Akanksha Jain, Divya Suri, Sophia Ling, Michelle Wong, Yong Zhang, Vardui Grigoryan, and Gabriel Shih.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Mara Mather at mara.mather{at}usc.edu

Funding

  • NIH

    R01AG057184

Other Version

  • previous version (February 22, 2022).
  • You are viewing the most recent version of this article.

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The Journal of Neuroscience: 42 (14)
Journal of Neuroscience
Vol. 42, Issue 14
6 Apr 2022
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Emotion Downregulation Targets Interoceptive Brain Regions While Emotion Upregulation Targets Other Affective Brain Regions
Jungwon Min, Kaoru Nashiro, Hyun Joo Yoo, Christine Cho, Padideh Nasseri, Shelby L. Bachman, Shai Porat, Julian F. Thayer, Catie Chang, Tae-Ho Lee, Mara Mather
Journal of Neuroscience 6 April 2022, 42 (14) 2973-2985; DOI: 10.1523/JNEUROSCI.1865-21.2022

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Emotion Downregulation Targets Interoceptive Brain Regions While Emotion Upregulation Targets Other Affective Brain Regions
Jungwon Min, Kaoru Nashiro, Hyun Joo Yoo, Christine Cho, Padideh Nasseri, Shelby L. Bachman, Shai Porat, Julian F. Thayer, Catie Chang, Tae-Ho Lee, Mara Mather
Journal of Neuroscience 6 April 2022, 42 (14) 2973-2985; DOI: 10.1523/JNEUROSCI.1865-21.2022
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Keywords

  • arousal
  • downregulation
  • emotion
  • fMRI
  • interoception
  • upregulation

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