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Featured ArticleResearch Articles, Cellular/Molecular

Role of Voltage-Gated K+ Channels and K2P Channels in Intrinsic Electrophysiological Properties and Saltatory Conduction at Nodes of Ranvier of Rat Lumbar Spinal Ventral Nerves

Sotatsu Tonomura and Jianguo G. Gu
Journal of Neuroscience 22 June 2022, 42 (25) 4980-4994; DOI: https://doi.org/10.1523/JNEUROSCI.0514-22.2022
Sotatsu Tonomura
Department of Anesthesiology and Perioperative Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294
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Jianguo G. Gu
Department of Anesthesiology and Perioperative Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0514-22.2022
PubMed 
35606142
Published By 
Society for Neuroscience
History 
  • Received March 14, 2022
  • Revision received May 2, 2022
  • Accepted May 17, 2022
  • First published May 23, 2022.
  • Version of record published June 22, 2022.
Copyright & Usage 
Copyright © 2022 the authors SfN exclusive license.

Author Information

  1. Sotatsu Tonomura and
  2. Jianguo G. Gu
  1. Department of Anesthesiology and Perioperative Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294
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Author contributions

  1. Author contributions: J.G.G. designed research; J.G.G. edited the paper; J.G.G. wrote the paper; S.T. performed research; S.T. analyzed data; S.T. wrote the first draft of the paper.

Disclosures

    • Received March 14, 2022.
    • Revision received May 2, 2022.
    • Accepted May 17, 2022.
  • This work was supported by National Institutes of Health Grants NS109059, DE018661, and DE023090 to J.G.G. We thank Dr. Ryan Vaden for reading and commenting on the previous version of this manuscript.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Jianguo G. Gu at jianguogu{at}uabmc.edu

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    NS109059
  • HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR)

    DE018661; DE023090

Other Version

  • previous version (May 23, 2022).
  • You are viewing the most recent version of this article.

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The Journal of Neuroscience: 42 (25)
Journal of Neuroscience
Vol. 42, Issue 25
22 Jun 2022
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Role of Voltage-Gated K+ Channels and K2P Channels in Intrinsic Electrophysiological Properties and Saltatory Conduction at Nodes of Ranvier of Rat Lumbar Spinal Ventral Nerves
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Role of Voltage-Gated K+ Channels and K2P Channels in Intrinsic Electrophysiological Properties and Saltatory Conduction at Nodes of Ranvier of Rat Lumbar Spinal Ventral Nerves
Sotatsu Tonomura, Jianguo G. Gu
Journal of Neuroscience 22 June 2022, 42 (25) 4980-4994; DOI: 10.1523/JNEUROSCI.0514-22.2022

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Role of Voltage-Gated K+ Channels and K2P Channels in Intrinsic Electrophysiological Properties and Saltatory Conduction at Nodes of Ranvier of Rat Lumbar Spinal Ventral Nerves
Sotatsu Tonomura, Jianguo G. Gu
Journal of Neuroscience 22 June 2022, 42 (25) 4980-4994; DOI: 10.1523/JNEUROSCI.0514-22.2022
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Keywords

  • action potential
  • node of Ranvier
  • patch-clamp recording
  • saltatory conduction
  • two-pore domain K+ channel
  • voltage-gated K+ channel

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