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Featured ArticleResearch Articles, Development/Plasticity/Repair

Understanding the Influence of Target Acquisition on Survival, Integration, and Phenotypic Maturation of Dopamine Neurons within Stem Cell-Derived Neural Grafts in a Parkinson's Disease Model

Niamh Moriarty, Jessica A. Kauhausen, Chiara Pavan, Cameron P.J. Hunt, Isabelle R. de Luzy, Vanessa Penna, Charlotte M. Ermine, Lachlan H. Thompson and Clare L. Parish
Journal of Neuroscience 22 June 2022, 42 (25) 4995-5006; DOI: https://doi.org/10.1523/JNEUROSCI.2431-21.2022
Niamh Moriarty
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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Jessica A. Kauhausen
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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Chiara Pavan
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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Cameron P.J. Hunt
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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Isabelle R. de Luzy
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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Vanessa Penna
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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Charlotte M. Ermine
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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Lachlan H. Thompson
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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  • ORCID record for Lachlan H. Thompson
Clare L. Parish
Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia
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The Journal of Neuroscience: 42 (25)
Journal of Neuroscience
Vol. 42, Issue 25
22 Jun 2022
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Understanding the Influence of Target Acquisition on Survival, Integration, and Phenotypic Maturation of Dopamine Neurons within Stem Cell-Derived Neural Grafts in a Parkinson's Disease Model
Niamh Moriarty, Jessica A. Kauhausen, Chiara Pavan, Cameron P.J. Hunt, Isabelle R. de Luzy, Vanessa Penna, Charlotte M. Ermine, Lachlan H. Thompson, Clare L. Parish
Journal of Neuroscience 22 June 2022, 42 (25) 4995-5006; DOI: 10.1523/JNEUROSCI.2431-21.2022

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Understanding the Influence of Target Acquisition on Survival, Integration, and Phenotypic Maturation of Dopamine Neurons within Stem Cell-Derived Neural Grafts in a Parkinson's Disease Model
Niamh Moriarty, Jessica A. Kauhausen, Chiara Pavan, Cameron P.J. Hunt, Isabelle R. de Luzy, Vanessa Penna, Charlotte M. Ermine, Lachlan H. Thompson, Clare L. Parish
Journal of Neuroscience 22 June 2022, 42 (25) 4995-5006; DOI: 10.1523/JNEUROSCI.2431-21.2022
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Keywords

  • dopamine
  • human pluripotent stem cells
  • Parkinson's disease
  • synaptic plasticity
  • target acquisition
  • transplantation

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