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Research Articles, Behavioral/Cognitive

Sustained Activity of Hippocampal Parvalbumin-Expressing Interneurons Supports Trace Eyeblink Conditioning in Mice

Rongrong Li, Weiwei Zhang, Jie Zhang, Haibo Zhang, Hui Chen, Zhian Hu, Zhongxiang Yao, Hao Chen and Bo Hu
Journal of Neuroscience 2 November 2022, 42 (44) 8343-8360; DOI: https://doi.org/10.1523/JNEUROSCI.0834-22.2022
Rongrong Li
1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
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Weiwei Zhang
1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
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  • ORCID record for Weiwei Zhang
Jie Zhang
1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
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Haibo Zhang
1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
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Hui Chen
1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
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Zhian Hu
1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
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Zhongxiang Yao
1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
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Hao Chen
2Experimental Center of Basic Medicine, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
3Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Army Medical University, Chongqing 400038, China
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Bo Hu
1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
3Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Army Medical University, Chongqing 400038, China
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0834-22.2022
PubMed 
36167784
Published By 
Society for Neuroscience
History 
  • Received April 30, 2022
  • Revision received August 25, 2022
  • Accepted September 23, 2022
  • First published September 27, 2022.
  • Version of record published November 2, 2022.
Copyright & Usage 
Copyright © 2022 the authors SfN exclusive license.

Author Information

  1. Rongrong Li1,*,
  2. Weiwei Zhang1,*,
  3. Jie Zhang1,*,
  4. Haibo Zhang1,
  5. Hui Chen1,
  6. Zhian Hu1,
  7. Zhongxiang Yao1,
  8. Hao Chen2,3, and
  9. Bo Hu1,3
  1. 1Department of Physiology, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
  2. 2Experimental Center of Basic Medicine, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China
  3. 3Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Army Medical University, Chongqing 400038, China
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Author contributions

  1. Author contributions: Z.Y., Hao C., and B.H. designed research; R.L., W.Z., J.Z., Hui C., Hao C., and B.H. performed research; R.L., W.Z., J.Z., H.Z., Hui C., Hao C., and B.H. analyzed data; H.Z. contributed unpublished reagents/analytic tools; Hao C., Z.Y. and B.H. wrote the paper.

  2. ↵*R.L., W.Z., and J.Z. contributed equally to this work.

View Full Text

Disclosures

    • Received April 30, 2022.
    • Revision received August 25, 2022.
    • Accepted September 23, 2022.
  • This work was supported by Natural Science Foundation of China Grants 81871039 to Hao C. and 82101561 to J.Z., Open Project Program of Brain and Intelligence Research Key Laboratory of Chongqing Education Commission Grant BIR2019001 to Hao C., Special Project on Improving Scientific and Technological Innovation Ability of Army Medical University Grant 2020XQN01 to Hao C., and Foundation for Innovative Research Groups of the National Natural Science Foundation of China Grant 31921003 to Z.H.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Bo Hu at bohu{at}tmmu.edu.cn or Hao Chen at haochen{at}tmmu.edu.cn

Funding

  • National Natural Science Foundation of China (NSFC)

    81871039; 82101561
  • Open Project Program of Brain and Intelligence Research Key Laboratory of Chongqing Education Commission

    BIR2019001
  • Special Project on Improving Scientific and Technological Innovation Ability of Army Medical University

    2020XQN01
  • Foundation for Innovative Research Groups of Natural Science Foundation of China

    31921003

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  • You are viewing the most recent version of this article.

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The Journal of Neuroscience: 42 (44)
Journal of Neuroscience
Vol. 42, Issue 44
2 Nov 2022
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Sustained Activity of Hippocampal Parvalbumin-Expressing Interneurons Supports Trace Eyeblink Conditioning in Mice
Rongrong Li, Weiwei Zhang, Jie Zhang, Haibo Zhang, Hui Chen, Zhian Hu, Zhongxiang Yao, Hao Chen, Bo Hu
Journal of Neuroscience 2 November 2022, 42 (44) 8343-8360; DOI: 10.1523/JNEUROSCI.0834-22.2022

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Sustained Activity of Hippocampal Parvalbumin-Expressing Interneurons Supports Trace Eyeblink Conditioning in Mice
Rongrong Li, Weiwei Zhang, Jie Zhang, Haibo Zhang, Hui Chen, Zhian Hu, Zhongxiang Yao, Hao Chen, Bo Hu
Journal of Neuroscience 2 November 2022, 42 (44) 8343-8360; DOI: 10.1523/JNEUROSCI.0834-22.2022
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Keywords

  • associative learning
  • hippocampus
  • interneuron
  • mouse
  • multichannel recording
  • trace conditioning

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