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Research Articles, Development/Plasticity/Repair

Olig2 Ablation in Immature Oligodendrocytes Does Not Enhance CNS Myelination and Remyelination

Jiajia Wang, Lijun Yang, Minqing Jiang, Chuntao Zhao, Xuezhao Liu, Kalen Berry, Ari Waisman, Abraham J. Langseth, Bennett G. Novitch, Dwight E. Bergles, Akiko Nishiyama and Q. Richard Lu
Journal of Neuroscience 9 November 2022, 42 (45) 8542-8555; https://doi.org/10.1523/JNEUROSCI.0237-22.2022
Jiajia Wang
1Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229
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Lijun Yang
1Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229
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Minqing Jiang
1Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229
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Chuntao Zhao
1Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229
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Xuezhao Liu
1Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229
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Kalen Berry
1Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229
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Ari Waisman
2Institute for Molecular Medicine, Langenbeckstrasse 1, Mainz, 55131, Germany
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Abraham J. Langseth
3The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
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Bennett G. Novitch
4Department of Neurobiology, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California 90095
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Dwight E. Bergles
3The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
5Johns Hopkins Kavli Neuroscience Discovery Institute, Baltimore, Maryland 21205
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Akiko Nishiyama
6Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut, 06269
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Q. Richard Lu
1Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229
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The Journal of Neuroscience: 42 (45)
Journal of Neuroscience
Vol. 42, Issue 45
9 Nov 2022
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Olig2 Ablation in Immature Oligodendrocytes Does Not Enhance CNS Myelination and Remyelination
Jiajia Wang, Lijun Yang, Minqing Jiang, Chuntao Zhao, Xuezhao Liu, Kalen Berry, Ari Waisman, Abraham J. Langseth, Bennett G. Novitch, Dwight E. Bergles, Akiko Nishiyama, Q. Richard Lu
Journal of Neuroscience 9 November 2022, 42 (45) 8542-8555; DOI: 10.1523/JNEUROSCI.0237-22.2022

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Olig2 Ablation in Immature Oligodendrocytes Does Not Enhance CNS Myelination and Remyelination
Jiajia Wang, Lijun Yang, Minqing Jiang, Chuntao Zhao, Xuezhao Liu, Kalen Berry, Ari Waisman, Abraham J. Langseth, Bennett G. Novitch, Dwight E. Bergles, Akiko Nishiyama, Q. Richard Lu
Journal of Neuroscience 9 November 2022, 42 (45) 8542-8555; DOI: 10.1523/JNEUROSCI.0237-22.2022
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Keywords

  • demyelination
  • myelination
  • Olig2
  • oligodendrocyte lineage
  • remyelination
  • white matter injury

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