This image shows a section of somatosensory cortex from an aged mouse 7 days after a diffuse traumatic brain injury. Reactive morphological restructuring of microglia (magenta) and astrocytes (cyan) is greater in these mice than in younger mice subjected to the same brain injury. For more information, see the article by Wangler, Bray et al. (pages 9082–9096). Cover image: Lynde Wangler.