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Research Articles, Neurobiology of Disease

Dual PI3Kδ/γ Inhibitor Duvelisib Prevents Development of Neuropathic Pain in Model of Paclitaxel-Induced Peripheral Neuropathy

Pavel Adamek, Mario Heles, Anirban Bhattacharyya, Monica Pontearso, Jakub Slepicka and Jiri Palecek
Journal of Neuroscience 2 March 2022, 42 (9) 1864-1881; DOI: https://doi.org/10.1523/JNEUROSCI.1324-21.2021
Pavel Adamek
Laboratory of Pain Research, Institute of Physiology of the Czech Academy of Sciences, Prague, 142 20, Czech Republic
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Mario Heles
Laboratory of Pain Research, Institute of Physiology of the Czech Academy of Sciences, Prague, 142 20, Czech Republic
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Anirban Bhattacharyya
Laboratory of Pain Research, Institute of Physiology of the Czech Academy of Sciences, Prague, 142 20, Czech Republic
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Monica Pontearso
Laboratory of Pain Research, Institute of Physiology of the Czech Academy of Sciences, Prague, 142 20, Czech Republic
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Jakub Slepicka
Laboratory of Pain Research, Institute of Physiology of the Czech Academy of Sciences, Prague, 142 20, Czech Republic
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Jiri Palecek
Laboratory of Pain Research, Institute of Physiology of the Czech Academy of Sciences, Prague, 142 20, Czech Republic
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The Journal of Neuroscience: 42 (9)
Journal of Neuroscience
Vol. 42, Issue 9
2 Mar 2022
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Dual PI3Kδ/γ Inhibitor Duvelisib Prevents Development of Neuropathic Pain in Model of Paclitaxel-Induced Peripheral Neuropathy
Pavel Adamek, Mario Heles, Anirban Bhattacharyya, Monica Pontearso, Jakub Slepicka, Jiri Palecek
Journal of Neuroscience 2 March 2022, 42 (9) 1864-1881; DOI: 10.1523/JNEUROSCI.1324-21.2021

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Dual PI3Kδ/γ Inhibitor Duvelisib Prevents Development of Neuropathic Pain in Model of Paclitaxel-Induced Peripheral Neuropathy
Pavel Adamek, Mario Heles, Anirban Bhattacharyya, Monica Pontearso, Jakub Slepicka, Jiri Palecek
Journal of Neuroscience 2 March 2022, 42 (9) 1864-1881; DOI: 10.1523/JNEUROSCI.1324-21.2021
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Keywords

  • dorsal horn
  • glycine
  • neuropathy
  • pain
  • PI3K
  • TRPV1

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