Deletion of Notch1 during Cochlear Maturation Leads to Rapid Supporting Cell Death and Profound Deafness

Alison Heffer; Felicia A. Gilels; Amy E. Kiernan

doi:10.1523/JNEUROSCI.1090-22.2022

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Deletion of Notch1 during Cochlear Maturation Leads to Rapid Supporting Cell Death and Profound Deafness

Alison Heffer, Felicia A. Gilels and Amy E. Kiernan

Journal of Neuroscience 11 January 2023, 43 (2) 199-210; DOI: https://doi.org/10.1523/JNEUROSCI.1090-22.2022

Alison Heffer

1Flaum Eye Institute, Department of Ophthalmology, University of Rochester Medical Center, Rochester, New York 14642

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Felicia A. Gilels

1Flaum Eye Institute, Department of Ophthalmology, University of Rochester Medical Center, Rochester, New York 14642

2Departments of Pathology and Laboratory Medicine

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Amy E. Kiernan

1Flaum Eye Institute, Department of Ophthalmology, University of Rochester Medical Center, Rochester, New York 14642

3Biomedical Genetics, University of Rochester Medical Center, Rochester, New York 14642

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Journal of Neuroscience

Vol. 43, Issue 2

11 Jan 2023

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Deletion of Notch1 during Cochlear Maturation Leads to Rapid Supporting Cell Death and Profound Deafness

Alison Heffer, Felicia A. Gilels, Amy E. Kiernan

Journal of Neuroscience 11 January 2023, 43 (2) 199-210; DOI: 10.1523/JNEUROSCI.1090-22.2022

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Deletion of Notch1 during Cochlear Maturation Leads to Rapid Supporting Cell Death and Profound Deafness

Alison Heffer, Felicia A. Gilels, Amy E. Kiernan

Journal of Neuroscience 11 January 2023, 43 (2) 199-210; DOI: 10.1523/JNEUROSCI.1090-22.2022

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cell death
cochlea
deafness
hair cells
Notch
supporting cells

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