Article Information
- Received December 5, 2022
- Revision received April 19, 2023
- Accepted May 25, 2023
- First published June 2, 2023.
- Version of record published July 5, 2023.
Author Information
- Hainan Lang1,*,
- Kenyaria V. Noble1,*,
- Jeremy L. Barth2,*,
- Jeffrey A. Rumschlag1,
- Tyreek R. Jenkins1,
- Shelby L. Storm1,
- Mark A. Eckert3,
- Judy R. Dubno3, and
- Bradley A. Schulte1
- 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina 29425
- 2Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, South Carolina 29425
- 3Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425
Author contributions
Author contributions: H.L. and K.V.N. designed research; H.L., K.V.N., and T.R.J. performed research; H.L., K.V.N., J.L.B., J.A.R., T.R.J., S.L.S., M.A.E., J.A.R., J.R.D., and B.A.S. analyzed data; H.L. wrote the first draft of the paper; H.L., K.V.N., J.L.B., J.A.R., T.R.J., S.L.S., M.A.E., J.A.R., J.R.D., and B.A.S. edited the paper.
↵*H.L., K.V.N. and J.L.B contributed equally to this work.
Disclosures
- Received December 5, 2022.
- Revision received April 19, 2023.
- Accepted May 25, 2023.
This work was supported in part by National Institutes of Health Grants P50 DC000422 (to H.L., J.R.D., B.A.S.), K18 DC018517 (to H.L.), T32 DC014435 (to K.V.N., T.R.J., J.A.R.), P30 GM103342 (to J.L.B.), and P20 GM103499 (to J.L.B.). Confocal image collection and analysis were done through Medical University of South Carolina (MUSC) Image facilities that were supported in part by the Cell and Molecular Imaging Shared Resource; the MUSC Cancer Center Support Grant P30 CA138313; SC COBRE Grants P20 GM103542 and P20 GM130457; the MUSC Core Center Grant P30 DK123704; and Shared Instrumentation Grants S10 OD018113 and S10 OD028663. Bioinformatic analysis of RNA-seq data was conducted through the MUSC Proteogenomics Facility (supported by P20 GM103499 and the MUSC Office of the Vice President for Research). We thank Nancy Smythe, Cindy Wang, Carlene Brandon, Gang Li, Nathaniel Parsons, Shabih Jafri, Juhong Zhu, and Jiaying Wu for their excellent technical assistance. We also thank Eric Hamlett and many Otolaryngology faculty and residents for their assistance with the collection and processing of human temporal bones. We thank Jayne Ahlstrom, Richard Schmiedt, Price Rainwater, and Federico Luricich for their suggestions and comments on the study and editing of the manuscript.
The authors declare no competing financial interests.
- Correspondence should be addressed to Hainan Lang at langh{at}musc.edu
Funding
NIH NIDCD
P30 GM103342NIH
P30 GM103342165 Ashley Avenue
T32 DC014435
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