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Research Articles, Systems/Circuits

2-AG-Mediated Control of GABAergic Signaling Is Impaired in a Model of Epilepsy

Roberto Colangeli, Maria Morena, Allison Werner, Roger J. Thompson, Mario van der Stelt, Quentin J. Pittman, Matthew N. Hill and G. Campbell Teskey
Journal of Neuroscience 25 January 2023, 43 (4) 571-583; DOI: https://doi.org/10.1523/JNEUROSCI.0541-22.2022
Roberto Colangeli
1Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary AB T2N4N1, Canada
2Department of Experimental and Clinical Medicine, Università Politecnica delle Marche, 60126 Ancona, Italy
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Maria Morena
1Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary AB T2N4N1, Canada
3Department of Physiology and Pharmacolgy, Sapienza University of Rome, 00185 Rome, Italy
4Neuropsychopharmacology Unit, Santa Lucia Foundation, 00143 Rome, Italy
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Allison Werner
1Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary AB T2N4N1, Canada
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Roger J. Thompson
1Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary AB T2N4N1, Canada
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Mario van der Stelt
5Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, 2333 CC, Leiden, The Netherlands
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Quentin J. Pittman
6Department of Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N4N1, Canada
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Matthew N. Hill
1Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary AB T2N4N1, Canada
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G. Campbell Teskey
1Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary AB T2N4N1, Canada
6Department of Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N4N1, Canada
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The Journal of Neuroscience: 43 (4)
Journal of Neuroscience
Vol. 43, Issue 4
25 Jan 2023
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2-AG-Mediated Control of GABAergic Signaling Is Impaired in a Model of Epilepsy
Roberto Colangeli, Maria Morena, Allison Werner, Roger J. Thompson, Mario van der Stelt, Quentin J. Pittman, Matthew N. Hill, G. Campbell Teskey
Journal of Neuroscience 25 January 2023, 43 (4) 571-583; DOI: 10.1523/JNEUROSCI.0541-22.2022

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2-AG-Mediated Control of GABAergic Signaling Is Impaired in a Model of Epilepsy
Roberto Colangeli, Maria Morena, Allison Werner, Roger J. Thompson, Mario van der Stelt, Quentin J. Pittman, Matthew N. Hill, G. Campbell Teskey
Journal of Neuroscience 25 January 2023, 43 (4) 571-583; DOI: 10.1523/JNEUROSCI.0541-22.2022
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Keywords

  • electrophysiology
  • endocannabinoids
  • epilepsy
  • GABA
  • kindling
  • synaptic plasticity

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