In the article, “Specific Plasticity Loci and Their Synergism Mediate Operant Conditioning,” by Yuto Momohara, Curtis L. Neveu, Hsin-Mei Chen, Douglas A. Baxter, and John H. Byrne, which appeared in the February 16, 2022 issue (pages 1211–1223), the diagram of the synaptic connections presented in Figure 5A1 was incorrect. The errors are only in the illustration of the circuit, but the correct circuit was used during simulations. These errors do not affect the results of the paper, and the online version has been corrected.