Pten(fl/fl)-Raptor(+/+)-Cre(–) Control | 1 | 5.6 (0) | 4.4 (0) | 0.0 | 0.0 | 0.0 | 239.4 | 0 | 0 |
2 | 5.3 (0) | 5.2 (0) | 3.1 (0) | 0.0 | 2.4 (0) | 381.4 | 0 | 0 |
3 | 5.0 (0) | 4.9 (0) | 1.8 (0) | 5.0 (0) | 2.1 (0) | 451.8 | 0 | 0 |
4 | 9.6 (0) | 6.3 (0) | 1.0 (0) | 4.8 (0) | 0.0 | 520 | 0 | 0 |
5 | 5.8 (0) | 4.6 (0) | 4.2 (0) | 5.5 (0) | 0.0 | 483.9 | 0 | 0 |
Pten(fl/fl)-Raptor(+/+)-Cre(+) | 1 | 6.7 (0) | 2.2 (0) | 5.7 (0) | 0.9 (0) | 0.0 | 371.5 | 0 | 0 |
2 | 3.7 (0) | 2.4 (0) | 1.2 (0) | 2.0 (0) | 0.0 | 223.3 | 0 | 0 |
3 | 6.2 (0) | 5.9 (0) | 9.7 (0) | 0.2 (0) | 0.0 | 528.8 | 0 | 0 |
4 | 5.5 (0) | 5.4 (0) | 1.0 (0) | 4.0 (0) | 6.5 (0) | 535.5 | 0 | 0 |
5 | 4.8 (4) | 1.0 (0) | 4.1 (0) | 0.0 | 0.0 | 235.9 | 4 | 0.017 |
Pten(fl/fl)-Rictor(+/+) or (+/fl) or (fl/fl)-Cre(–) Control | 1 | 3.0 (0) | 0.0 | 2.3 (0) | 0.0 | 2.8 (0) | 194.5 | 0 | 0 |
2 | 3.7 (0) | 2.3 (0) | 0.0 | 0.0 | 2.4 (0) | 200.6 | 0 | 0 |
3 | 4.7 (0) | 3.5 (0) | 2.0 (0) | 0.0 | 0.0 | 245.4 | 0 | 0 |
4 | 6.0 (0) | 0.2 (0) | 0.0 | 3.1 (0) | 0.0 | 225.6 | 0 | 0 |
5 | 5.0 (0) | 0.0 | 1.7 (0) | 0.0 | 2.8 (0) | 229.3 | 0 | 0 |
6 | 5.2 (0) | 5.8 (0) | 0.0 | 2.3 (0) | 0.0 | 318.8 | 0 | 0 |
7 | 6.5 (0) | 4.1 (0) | 0.0 | 2.9 (0) | 0.0 | 323.5 | 0 | 0 |
Pten(fl/fl)-Rictor(+/+)-Cre(+) | 1 | 3.3 (0) | 3.3 (0) | 1.2 (0) | 0.0 | 0.0 | 188.1 | 0 | 0 |
2 | 4.7 (0) | 3.2 (0) | 0.7 (0) | 0.2 (0) | 0.0 | 211.2 | 0 | 0 |
3 | 1.0 (0) | 3.2 (1) | 2.7 (0) | 2.5 (2) | 0.0 | 226 | 3 | 0.013 |
4 | 7.1 (0) | 0.2 (0) | 2.2 (0) | 4.4 (0) | 0.0 | 334.8 | 0 | 0 |
Pten(fl/fl)-Rictor(fl/fl)-Cre(+) | 1 | 2.2 (0) | 0.0 | 2.2 (0) | 1.8 (0) | 0.0 | 148.5 | 0 | 0 |
2 | 0.0 | 1.3 (1) | 5.1 (8) | 0.0 | 0.0 | 154 | 9 | 0.058 |
3 | 1.7 (0) | 0.0 | 3.1 (2) | 3.2 (1) | 0.0 | 190 | 3 | 0.016 |
4 | 3.4 (0) | 6.2 (0) | 0.0 | 0.0 | 0.0 | 228.9 | 0 | 0 |
5 | 7.0 (0) | 6.4 (0) | 3.2 (0) | 1.1 (0) | 1.8 (0) | 470.2 | 0 | 0 |
Pten(+/+)-Cre(+) (Original Line Control) | 1 | 0.0 | 0.0 | 1.3 (0) | 0.0 | 2.8 (0) | 97.3 | 0 | 0 |
2 | 3.4 (0) | 2.3 (0) | 0.0 | 0.0 | 0.0 | 139.1 | 0 | 0 |
Pten(fl/fl)-Cre(+) (Original Line Pten KO) | 1 | 4.0 (8) | 0.0 | 0.0 | 0.0 | 0.0 | 95.3 | 8 | 0.084 |
2 | 7.1 (6) | 0.1 (0) | 0.0 | 0.0 | 0.0 | 172.8 | 6 | 0.035 |