Language Experience during Infancy Predicts White Matter Myelination at Age 2 Years

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¹Institute for Learning & Brain Sciences, University of Washington, Seattle, Washington 98195
²Department of Radiology, University of Washington, Seattle, Washington 98195
³Department of Linguistics, University of Washington, Seattle, Washington 98195
⁴Department of Speech & Hearing Sciences, University of Washington, Seattle, Washington 98195

Author contributions: E.H., N.F.R., and P.K.K. designed research; E.H., N.F.R., and P.K.K. performed research; E.H. and N.M.C. analyzed data; E.H. wrote the first draft of the paper; N.M.C., V.L.Y., N.F.R., and P.K.K. edited the paper; V.L.Y. developed and piloted the MR imaging protocols and contributed unpublished reagents/analytic tools.

This work was supported by the Overdeck Family Foundation, the Bezos Family Foundation, and the University of Washington Institute for Learning & Brain Sciences Infants to Adolescents Project. Software for macro-molecular proton fraction map reconstruction was distributed under support of the National Institutes of Health High-Impact Neuroscience Research Resource Grant R24NS104098. We thank Margaux Bouchegnies, Spencer Bowen, Amy Busch, Ruofan Cai, Nicole Miles Dunn, Karen Edlefsen, Kyli McGillivray, Hollis Helton, Sarah Hillegass, Rachel Kinsinger, Anna Kunz, Julia Mizrahi, Annique Nyman, Denise Padden, A’Dawnah Pangelinan, Brooke Peterson, Laura Purdy, Stephanie Purdy, Nour Shoora, and Bo Woo for assistance in participant recruitment, data collection, and coding of the home language recordings.
The authors declare no competing financial interests.
Correspondence should be addressed to Elizabeth Huber at ehuber{at}uw.edu