Pictured are overlayed confocal images of mouse dorsal root ganglion neurons (DRGNs) labeled with antibodies against calcium sensor caldendrin (purple), a marker for mechanically sensitive DRGNs (neurofilament 200, blue), and calcitonin gene related peptide parvalbumin (green). This technique revealed that caldendrin is highly expressed in mechanically sensitive DRGNs, similar to mechanically active receptors that play a role in touch sensation (PIEZO2). See the article by Josue Lopez et al. for more information on how caldendrin interacts with this receptor to impact touch sensation. Cover image: Wes Maddox and Josue Lopez.