A part of the vagus nerve called the nodose ganglia contains viscerosensory neurons that play key roles in many homeostatic behaviors to keep us alive as well as glial cells that support these neurons. An immunohistology experiment that labeled all vagal neurons (Tubb3+, magenta) and cells that derive from the neural crest but have a history of Phox2b expression (GFP+, cyan) from a Wnt1^Cre;Phox2b^FlpO;R26n^GFP mouse shows that GFP+ cells were non-neuronal (Tubb3 negative) and were located specifically in the nodose ganglia. This experiment supported the finding that many of the nodose, but not jugular, glial cells that derive from the neural crest have a unique history of transient expression of the homeobox transcription factor Phox2b. See the article by Elijah Lowenstein et al. for more information on their investigation into the genetic program governing the development of nodose glial cells, as well as their molecular characterization of nodose glial cell heterogeneity. Cover image: Elijah Lowenstein.