Article Information
- Received January 30, 2024
- Revision received May 7, 2024
- Accepted May 29, 2024
- First published June 12, 2024.
- Version of record published July 31, 2024.
Author Information
- Da Lin1,
- Andrew Gold2,
- Sarah Kaye1,
- Jeffrey R. Atkinson3,
- Marcus Tol4,
- Andrew Sas3,
- Benjamin Segal3,
- Peter Tontonoz4,
- Jiangjiang Zhu2, and
- Jie Gao1
- 1Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210
- 2Department of Human Sciences, The Ohio State University, Columbus, Ohio 43210
- 3Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210
- 4Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, California 90095
Author contributions
Author contributions: D.L. and J.G. designed research; D.L., A.G., S.K., J.R.A., J.Z., and J.G. performed research; P.T. contributed unpublished reagents/analytic tools; D.L., A.G., S.K., J.R.A., M.T., A.S., B.S., P.T., J.Z., and J.G. analyzed data; D.L. and J.G. wrote the paper.
Disclosures
- Received January 30, 2024.
- Revision received May 7, 2024.
- Accepted May 29, 2024.
We thank Dr. Takaomi C. Saido in RIKEN Center for Brain Science Institute, Wako, Japan, for kindly sharing AppNL-GF mice, Cami Webb and Grace Poturalski for technical support on the project, and Emma Wang for genotyping and mouse care. This research was supported by National Institutes of Health (NIH) grants R01AG073310 (to J.G.) and Edward N. and Della L. Thome Memorial Foundation Awards for Alzheimer research (to J.G.). The analysis was also partially supported by NIH grant R35GM133510 (to J.Z.) and The Ohio State University's University Graduate Fellowship (to A.G.).
The authors declare no competing financial interests.
- Correspondence should be addressed to Jie Gao at Jie.Gao{at}osumc.edu.
Funding
HHS | NIH | National Institute on Aging (NIA)
R01 AG073310Edward N. and Della L. Thome Memorial Foundation (Thome Memorial Foundation)
HHS | National Institutes of Health (NIH)
R35 GM133510
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