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Featured ArticleResearch Articles, Systems/Circuits

The Volitional Control of Individual Motor Units Is Constrained within Low-Dimensional Neural Manifolds by Common Inputs

Julien Rossato, Simon Avrillon, Kylie Tucker, Dario Farina and François Hug
Journal of Neuroscience 21 August 2024, 44 (34) e0702242024; https://doi.org/10.1523/JNEUROSCI.0702-24.2024
Julien Rossato
1Laboratory “Movement, Interactions, Performance” (UR 4334), Nantes Université, Nantes, France
2Laboratory of Neuromotor Physiology, IRCCS Fondazione Santa Lucia, Rome, Italy
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Simon Avrillon
3Department of Bioengineering, Faculty of Engineering, Imperial College London, London, United Kingdom
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Kylie Tucker
4School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland, Australia
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Dario Farina
3Department of Bioengineering, Faculty of Engineering, Imperial College London, London, United Kingdom
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François Hug
4School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland, Australia
5LAMHESS, Université Côte d'Azur, Nice, France
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0702-24.2024
PubMed 
38951036
Published By 
Society for Neuroscience
History 
  • Received April 8, 2024
  • Revision received June 4, 2024
  • Accepted June 21, 2024
  • First published July 1, 2024.
  • Version of record published August 21, 2024.
Copyright & Usage 
Copyright © 2024 the authors SfN exclusive license.

Author Information

  1. Julien Rossato1,2,
  2. Simon Avrillon3,
  3. Kylie Tucker4,
  4. Dario Farina3, and
  5. François Hug4,5
  1. 1Laboratory “Movement, Interactions, Performance” (UR 4334), Nantes Université, Nantes, France
  2. 2Laboratory of Neuromotor Physiology, IRCCS Fondazione Santa Lucia, Rome, Italy
  3. 3Department of Bioengineering, Faculty of Engineering, Imperial College London, London, United Kingdom
  4. 4School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland, Australia
  5. 5LAMHESS, Université Côte d'Azur, Nice, France
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Author contributions

  1. Author contributions: J.R., S.A., K.T., D.F., and F.H. designed research; J.R. performed research; J.R. and S.A. contributed unpublished reagents/analytic tools; J.R. and S.A. analyzed data; J.R., S.A., K.T., D.F., and F.H. wrote the paper.

Disclosures

    • Received April 8, 2024.
    • Revision received June 4, 2024.
    • Accepted June 21, 2024.
  • F.H. is supported by the French government, through the UCAJEDI Investments in the Future project managed by the National Research Agency (ANR) with the reference number ANR-15-IDEX-01 and by an ANR grant (ANR-19-CE17-002-01, COMMODE project). D.F. is supported by the European Research Council Synergy Grant NaturalBionicS (contract #810346), the EPSRC Transformative Healthcare, NISNEM Technology (EP/T020970), and the BBSRC, “Neural Commands for Fast Movements in the Primate Motor System” (NU-003743).

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to at François Hug to francois.hug{at}univ-cotedazur.fr.

Funding

  • Agence Nationale de la Recherche (ANR)

    ANR-15-IDEX-01; ANR-19-CE17-002-01
  • EC | ERC | HORIZON EUROPE European Research Council (ERC)

    810346
  • UKRI | Biotechnology and Biological Sciences Research Council (BBSRC)

    NU-003743

Other Version

  • previous version (July 01, 2024).
  • You are viewing the most recent version of this article.

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Jul 20241528087
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Oct 20241702121
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In this issue

The Journal of Neuroscience: 44 (34)
Journal of Neuroscience
Vol. 44, Issue 34
21 Aug 2024
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The Volitional Control of Individual Motor Units Is Constrained within Low-Dimensional Neural Manifolds by Common Inputs
Julien Rossato, Simon Avrillon, Kylie Tucker, Dario Farina, François Hug
Journal of Neuroscience 21 August 2024, 44 (34) e0702242024; DOI: 10.1523/JNEUROSCI.0702-24.2024

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The Volitional Control of Individual Motor Units Is Constrained within Low-Dimensional Neural Manifolds by Common Inputs
Julien Rossato, Simon Avrillon, Kylie Tucker, Dario Farina, François Hug
Journal of Neuroscience 21 August 2024, 44 (34) e0702242024; DOI: 10.1523/JNEUROSCI.0702-24.2024
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Keywords

  • electromyography
  • module
  • motor neuron
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  • synergy

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