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Research Articles, Neurobiology of Disease

Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers

Balaji Krishnan, Michela Marcatti, Anna Fracassi, Wen-Ru Zhang, Jutatip Guptarak, Kathia Johnson, Auston Grant, Rakez Kayed, Giulio Taglialatela and Maria-Adelaide Micci
Journal of Neuroscience 16 April 2025, 45 (16) e1664242025; https://doi.org/10.1523/JNEUROSCI.1664-24.2025
Balaji Krishnan
1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555
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Michela Marcatti
1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555
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Anna Fracassi
1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555
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Wen-Ru Zhang
1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555
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Jutatip Guptarak
1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555
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Kathia Johnson
2Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas 77555
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Auston Grant
2Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas 77555
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Rakez Kayed
1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555
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Giulio Taglialatela
1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555
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Maria-Adelaide Micci
2Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas 77555
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The Journal of Neuroscience: 45 (16)
Journal of Neuroscience
Vol. 45, Issue 16
16 Apr 2025
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Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers
Balaji Krishnan, Michela Marcatti, Anna Fracassi, Wen-Ru Zhang, Jutatip Guptarak, Kathia Johnson, Auston Grant, Rakez Kayed, Giulio Taglialatela, Maria-Adelaide Micci
Journal of Neuroscience 16 April 2025, 45 (16) e1664242025; DOI: 10.1523/JNEUROSCI.1664-24.2025

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Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers
Balaji Krishnan, Michela Marcatti, Anna Fracassi, Wen-Ru Zhang, Jutatip Guptarak, Kathia Johnson, Auston Grant, Rakez Kayed, Giulio Taglialatela, Maria-Adelaide Micci
Journal of Neuroscience 16 April 2025, 45 (16) e1664242025; DOI: 10.1523/JNEUROSCI.1664-24.2025
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Keywords

  • Alzheimer's disease
  • exosomes
  • neural stem cells
  • synapses
  • Tau oligomers
  • miRNAs

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