Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers

Balaji Krishnan; Michela Marcatti; Anna Fracassi; Wen-Ru Zhang; Jutatip Guptarak; Kathia Johnson; Auston Grant; Rakez Kayed; Giulio Taglialatela; Maria-Adelaide Micci

doi:10.1523/JNEUROSCI.1664-24.2025

Research Articles, Neurobiology of Disease

Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers

Balaji Krishnan, Michela Marcatti, Anna Fracassi, Wen-Ru Zhang, Jutatip Guptarak, Kathia Johnson, Auston Grant, Rakez Kayed, Giulio Taglialatela and Maria-Adelaide Micci

Journal of Neuroscience 16 April 2025, 45 (16) e1664242025; https://doi.org/10.1523/JNEUROSCI.1664-24.2025

Balaji Krishnan

1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Balaji Krishnan

Michela Marcatti

1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Anna Fracassi

1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Wen-Ru Zhang

1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jutatip Guptarak

1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kathia Johnson

2Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Auston Grant

2Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Rakez Kayed

1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Giulio Taglialatela

1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Maria-Adelaide Micci

2Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas 77555

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Maria-Adelaide Micci

Article
Figures & Data
Info & Metrics
eLetters
Peer Review
PDF

You are using an old browser, click here to download PDF

PDF Container

In this issue

Journal of Neuroscience

Vol. 45, Issue 16

16 Apr 2025

Table of Contents
About the Cover
Index by author
Masthead (PDF)

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers

Message Subject (Your Name) has forwarded a page to you from Journal of Neuroscience

Message Body (Your Name) thought you would be interested in this article in Journal of Neuroscience.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

View Full Page PDF

Citation Tools

Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers

Balaji Krishnan, Michela Marcatti, Anna Fracassi, Wen-Ru Zhang, Jutatip Guptarak, Kathia Johnson, Auston Grant, Rakez Kayed, Giulio Taglialatela, Maria-Adelaide Micci

Journal of Neuroscience 16 April 2025, 45 (16) e1664242025; DOI: 10.1523/JNEUROSCI.1664-24.2025

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Respond to this article

Request Permissions

Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers

Balaji Krishnan, Michela Marcatti, Anna Fracassi, Wen-Ru Zhang, Jutatip Guptarak, Kathia Johnson, Auston Grant, Rakez Kayed, Giulio Taglialatela, Maria-Adelaide Micci

Journal of Neuroscience 16 April 2025, 45 (16) e1664242025; DOI: 10.1523/JNEUROSCI.1664-24.2025

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Jump to section

Article
Figures & Data
Info & Metrics
eLetters
Peer Review
PDF

Keywords

Alzheimer's disease
exosomes
neural stem cells
synapses
Tau oligomers
miRNAs

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Cited By...

Research Articles

Brain-behavior differences in pre-modern and modern lineages of domestic dogs
Microglia supports both the singular form of LTP expressed by the lateral perforant path and episodic memory
Inhibition of Rho-associated kinases ROCK1 and ROCK2 as a Therapeutic Strategy to Reactivate the Repressed FXN Gene in Friedreich Ataxia

Show more Research Articles

Neurobiology of Disease

Brain Topological Changes in Subjective Cognitive Decline and Associations with Amyloid Stages
Inhibition of Rho-associated kinases ROCK1 and ROCK2 as a Therapeutic Strategy to Reactivate the Repressed FXN Gene in Friedreich Ataxia
Threonine-53 phosphorylation of dopamine transporter dictates kappa opioid receptor mediated locomotor suppression, aversion, and cocaine reward

Show more Neurobiology of Disease

Main menu

User menu

Search

Hippocampal Neural Stem Cell Exosomes Promote Brain Resilience against the Impact of Tau Oligomers

In this issue

Citation Manager Formats

Keywords

Responses to this article

Jump to comment:

Related Articles

Cited By...

More in this TOC Section

Research Articles

Neurobiology of Disease