Shown is a genetically mutated zebrafish larva's otic vesicle, which is a bundle of cells that eventually develops into the inner ear. This larva was bred to have genes for two kinds of epithelial splicing-regulatory proteins (Esrp1 and Esrp2) deleted in a study on the role these proteins play in hair cell development and function. Inner ear hair cells residing in the cristae of three semicircular canals were labeled with GFP (green). F-actin was labeled with phalloidin (magenta). This experimental strategy revealed that loss of Esrp1 and Esrp2 does not affect how hair cells develop in the semicircular canals of zebrafish. See the article by Xuebo Yao et al. for more information. Cover image: Xuebo Yao.