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Journal Club

A Novel APP Knock-In Mouse Model to Study the Protective Effects of the Icelandic Mutation In Vivo

Maria Luisa Valle
Journal of Neuroscience 23 April 2025, 45 (17) e0164252025; https://doi.org/10.1523/JNEUROSCI.0164-25.2025
Maria Luisa Valle
Department of Pathology, New York University Grossman School of Medicine, New York, New York 10016
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0164-25.2025
PubMed 
40268492
Published By 
Society for Neuroscience
History 
  • Received January 23, 2025
  • Revision received March 5, 2025
  • Accepted March 5, 2025
  • First published April 23, 2025.
  • Version of record published April 23, 2025.
Copyright & Usage 
Copyright © 2025 the authors SfN exclusive license.

Author Information

  1. Maria Luisa Valle
  1. Department of Pathology, New York University Grossman School of Medicine, New York, New York 10016
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Author contributions

Disclosures

    • Received January 23, 2025.
    • Revision received March 5, 2025.
    • Accepted March 5, 2025.
  • I thank Dr. Jorge Ghiso and Dr. Agueda Rostagno for feedback on this manuscript and Dr. Teresa Esch for editorial revisions and comments.

  • This Journal Club was mentored by Jorge Ghiso and Agueda Rostagno.

  • The author declares no competing financial interests.

  • Review of Shimohama et al.

  • Editor’s Note: These short reviews of recent JNeurosci articles, written exclusively by students or postdoctoral fellows, summarize the important findings of the paper and provide additional insight and commentary. If the authors of the highlighted article have written a response to the Journal Club, the response can be found by viewing the Journal Club at www.jneurosci.org. For more information on the format, review process, and purpose of Journal Club articles, please see http://jneurosci.org/content/jneurosci-journal-club.

  • Correspondence should be addressed to Maria Luisa Valle at maria.valle{at}nyulangone.org.

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The Journal of Neuroscience: 45 (17)
Journal of Neuroscience
Vol. 45, Issue 17
23 Apr 2025
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A Novel APP Knock-In Mouse Model to Study the Protective Effects of the Icelandic Mutation In Vivo
Maria Luisa Valle
Journal of Neuroscience 23 April 2025, 45 (17) e0164252025; DOI: 10.1523/JNEUROSCI.0164-25.2025

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A Novel APP Knock-In Mouse Model to Study the Protective Effects of the Icelandic Mutation In Vivo
Maria Luisa Valle
Journal of Neuroscience 23 April 2025, 45 (17) e0164252025; DOI: 10.1523/JNEUROSCI.0164-25.2025
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