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History
- Received February 6, 2025
- Revision received July 2, 2025
- Accepted July 23, 2025
- First published September 9, 2025.
- Version of record published October 22, 2025.
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Copyright © 2025 the authors SfN exclusive license.
Author Information
Author contributions
Author contributions: O.T. and A.J.F. designed research; O.T. and L.E.K. performed research; O.T. and L.E.K. analyzed data; O.T., H.M.E., and A.J.F. wrote the paper.
Disclosures
- Received February 6, 2025.
- Revision received July 2, 2025.
- Accepted July 23, 2025.
We thank Timothy Hla for providing the Sphk1f/f and S1pr1f/f mice. We also thank Dr. Ed Levine for providing the Rlbp1-CreERT mice and Dr. Dennis Guttridge for providing the NFκB-eGFP reporter mice.
This work was supported by the National Eye Institute R01 EY032141-05 (A.J.F.).
The authors declare no competing financial interests.
This paper contains supplemental material available at: https://doi.org/10.1523/JNEUROSCI.0150-25.2025
- Correspondence should be addressed to Andy J. Fischer at andrew.fischer{at}osumc.edu.
Funding
HHS | NIH | National Eye Institute (NEI)
EY032141-05
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