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Featured ArticleResearch Articles, Systems/Circuits

Kappa Opioid Receptors Control a Stress-Sensitive Brain Circuit and Drive Cocaine Seeking

Valentina Martinez Damonte, Lydia G. Bailey, Amit Thakar, Joanna Stralka, Travis E. Brown and Julie A. Kauer
Journal of Neuroscience 22 October 2025, 45 (43) e1233252025; https://doi.org/10.1523/JNEUROSCI.1233-25.2025
Valentina Martinez Damonte
1Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University, Stanford, California 94305
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Lydia G. Bailey
2Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington 99163
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Amit Thakar
2Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington 99163
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Joanna Stralka
1Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University, Stanford, California 94305
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Travis E. Brown
2Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington 99163
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Julie A. Kauer
1Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University, Stanford, California 94305
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The Journal of Neuroscience: 45 (43)
Journal of Neuroscience
Vol. 45, Issue 43
22 Oct 2025
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Kappa Opioid Receptors Control a Stress-Sensitive Brain Circuit and Drive Cocaine Seeking
Valentina Martinez Damonte, Lydia G. Bailey, Amit Thakar, Joanna Stralka, Travis E. Brown, Julie A. Kauer
Journal of Neuroscience 22 October 2025, 45 (43) e1233252025; DOI: 10.1523/JNEUROSCI.1233-25.2025

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Kappa Opioid Receptors Control a Stress-Sensitive Brain Circuit and Drive Cocaine Seeking
Valentina Martinez Damonte, Lydia G. Bailey, Amit Thakar, Joanna Stralka, Travis E. Brown, Julie A. Kauer
Journal of Neuroscience 22 October 2025, 45 (43) e1233252025; DOI: 10.1523/JNEUROSCI.1233-25.2025
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Keywords

  • LTP
  • nucleus accumbens
  • optogenetics
  • plasticity
  • self-administration
  • ventral tegmental area

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Research Articles

  • Too little and too much: balanced hippocampal, but not medial prefrontal, neural activity is required for intact novel object recognition in rats
  • Structural plasticity of peptidergic and nonpeptidergic C afferent terminals in the medullary dorsal horn during craniofacial inflammatory pain
  • Comparison of signals from cerebellar Purkinje cells and deep nuclei during temporal prediction in primates
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Systems/Circuits

  • Structural plasticity of peptidergic and nonpeptidergic C afferent terminals in the medullary dorsal horn during craniofacial inflammatory pain
  • Comparison of signals from cerebellar Purkinje cells and deep nuclei during temporal prediction in primates
  • Energy Deficit is a Key Driver of Sleep Homeostasis
Show more Systems/Circuits
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