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Research Articles, Cellular/Molecular

Intrinsic Dendritic Integration Features of Prefrontal Layer 5 Pyramidal Cell Subclasses

Selin Schamiloglu, Rebecca L. Clarkson, Natalia S. Stone, Alayna T. Liptak and Kevin J. Bender
Journal of Neuroscience 26 November 2025, 45 (48) e1080252025; https://doi.org/10.1523/JNEUROSCI.1080-25.2025
Selin Schamiloglu
1Neuroscience Graduate Program, University of California, San Francisco, California 94158
2Center for Integrative Neuroscience, Kavli Institute for Fundamental Neuroscience, Department of Neurology, University of California, San Francisco, California 94158
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  • ORCID record for Selin Schamiloglu
Rebecca L. Clarkson
1Neuroscience Graduate Program, University of California, San Francisco, California 94158
2Center for Integrative Neuroscience, Kavli Institute for Fundamental Neuroscience, Department of Neurology, University of California, San Francisco, California 94158
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Natalia S. Stone
2Center for Integrative Neuroscience, Kavli Institute for Fundamental Neuroscience, Department of Neurology, University of California, San Francisco, California 94158
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Alayna T. Liptak
2Center for Integrative Neuroscience, Kavli Institute for Fundamental Neuroscience, Department of Neurology, University of California, San Francisco, California 94158
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Kevin J. Bender
2Center for Integrative Neuroscience, Kavli Institute for Fundamental Neuroscience, Department of Neurology, University of California, San Francisco, California 94158
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1080-25.2025
PubMed 
41093758
Published By 
Society for Neuroscience
History 
  • Received May 30, 2025
  • Revision received October 3, 2025
  • Accepted October 8, 2025
  • First published October 15, 2025.
  • Version of record published November 26, 2025.
Copyright & Usage 
Copyright © 2025 the authors SfN exclusive license.

Author Information

  1. Selin Schamiloglu1,2,
  2. Rebecca L. Clarkson1,2,
  3. Natalia S. Stone2,
  4. Alayna T. Liptak2, and
  5. Kevin J. Bender2
  1. 1Neuroscience Graduate Program, University of California, San Francisco, California 94158
  2. 2Center for Integrative Neuroscience, Kavli Institute for Fundamental Neuroscience, Department of Neurology, University of California, San Francisco, California 94158
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Author contributions

  1. Author contributions: S.S., R.L.C., and K.J.B. designed research; S.S., R.L.C., and K.J.B. performed research; S.S., R.L.C., N.S.S., A.T.L., and K.J.B. analyzed data.

Disclosures

    • Received May 30, 2025.
    • Revision received October 3, 2025.
    • Accepted October 8, 2025.
  • We thank members of the Bender lab for their helpful discussions and feedback. This work was supported by National Institutes of Health Grants DA035913 and MH25978.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Kevin J. Bender at kevin.bender{at}ucsf.edu.

Funding

  • HHS | NIH | National Institute of Mental Health (NIMH)

    MH25978
  • HHS | NIH | National Institute on Drug Abuse (NIDA)

    DA035913

Other Version

  • previous version (October 15, 2025).
  • You are viewing the most recent version of this article.

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The Journal of Neuroscience: 45 (48)
Journal of Neuroscience
Vol. 45, Issue 48
26 Nov 2025
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Intrinsic Dendritic Integration Features of Prefrontal Layer 5 Pyramidal Cell Subclasses
Selin Schamiloglu, Rebecca L. Clarkson, Natalia S. Stone, Alayna T. Liptak, Kevin J. Bender
Journal of Neuroscience 26 November 2025, 45 (48) e1080252025; DOI: 10.1523/JNEUROSCI.1080-25.2025

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Intrinsic Dendritic Integration Features of Prefrontal Layer 5 Pyramidal Cell Subclasses
Selin Schamiloglu, Rebecca L. Clarkson, Natalia S. Stone, Alayna T. Liptak, Kevin J. Bender
Journal of Neuroscience 26 November 2025, 45 (48) e1080252025; DOI: 10.1523/JNEUROSCI.1080-25.2025
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Keywords

  • backpropagation
  • calcium channel
  • dendrite
  • integration

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