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Articles

Fluorescent probes that stain living nerve terminals

L Magrassi, D Purves and JW Lichtman
Journal of Neuroscience 1 April 1987, 7 (4) 1207-1214; https://doi.org/10.1523/JNEUROSCI.07-04-01207.1987
L Magrassi
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D Purves
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JW Lichtman
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Abstract

We have evaluated the efficacy of 18 cationic mitochondrial dyes that, as a class, show some ability to stain living nerve terminals. Several of these agents provide excellent staining of neuromuscular junctions in a wide range of species. More detailed studies of the most effective of these dyes--4-(4-diethylaminostyryl)-N-methylpyridinium iodide (4-Di- 2-ASP)--indicate that it has no lasting effect on the structure or function of motor nerve terminals. As demonstrated in the accompanying paper (Lichtman et al., 1987; see also Lichtman et al., 1986), 4-Di-2- ASP can therefore be used to follow the configuration of identified motor terminals over arbitrarily long intervals.

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The Journal of Neuroscience: 7 (4)
Journal of Neuroscience
Vol. 7, Issue 4
1 Apr 1987
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Fluorescent probes that stain living nerve terminals
L Magrassi, D Purves, JW Lichtman
Journal of Neuroscience 1 April 1987, 7 (4) 1207-1214; DOI: 10.1523/JNEUROSCI.07-04-01207.1987

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Fluorescent probes that stain living nerve terminals
L Magrassi, D Purves, JW Lichtman
Journal of Neuroscience 1 April 1987, 7 (4) 1207-1214; DOI: 10.1523/JNEUROSCI.07-04-01207.1987
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