Article Information
- Received October 9, 2019
- Revision received November 11, 2019
- Accepted November 14, 2019
- First published November 21, 2019.
- Version of record published January 8, 2020.
Author Information
Author contributions
Author contributions: E.M., R.F., V.B.-R., T.M.S., T.S.T., and K.A.S. performed research; E.M., R.F., V.B.-R., T.M.S., M.L.O., and V.J.T. analyzed data; E.M. wrote the first draft of the paper; E.M., J.R.B., and V.J.T. wrote the paper; M.L.O. edited the paper; J.R.B. and V.J.T. designed research.
Disclosures
- Received October 9, 2019.
- Revision received November 11, 2019.
- Accepted November 14, 2019.
This work was supported by the National Institutes of Health (Grant R01 NS106908 to V.J.T. and J.R.B., Grant R01 NS111761 to J.R.B and V.J.T., Grant R01 NS085426 to V.J.T., and Grant R01 NS051709 to J.R.B.), the Craig H. Neilsen Foundation (Grant 382566 to V.J.T.), and the Drexel University Dean's Fellowship for Excellence in Collaborative or Themed Research Training (E.M.). We thank David E. Szymkowski of Xencor for supplying XPro1595; Jim Burns, Garth Ehrlich, Alison Carey, and their lab members for advice, training, and resources for the bacteriology experiments; Michael Lane and his lab members for advice and training for intubating the rodents; Alexander G. Rabchevsky for providing the MATLAB algorithm that served as the basis for what we used to analyze the naturally occurring events; Vladimir Zhukarev for assistance with the confocal microscope; the Marion Murray Drexel University Spinal Cord Research Center for use of its core facilities; and the Center for Neuroanatomy with Neurotrophic (supported by NIH Grant P40 OD010996) for providing the PRV-Bartha.
The authors declare no competing financial interests.
- Please address all correspondence to John R. Bethea at jrb445{at}drexel.edu or Veronica J. Tom at vjt25{at}drexel.edu
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