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Research Articles, Behavioral/Cognitive

Blunted Expected Reward Value Signals in Binge Alcohol Drinkers

Serenella Tolomeo, Alex Baldacchino and J. Douglas Steele
Journal of Neuroscience 30 January 2023, JN-RM-2157-21; DOI: https://doi.org/10.1523/JNEUROSCI.2157-21.2022
Serenella Tolomeo
1Institute of High Performance Computing, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore;
2Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;
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Alex Baldacchino
3Division of Population and Behavioral Science, Medical School, University of St Andrews, United Kingdom;
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J. Douglas Steele
4Division of Imaging Science and Technology, Medical School, University of Dundee, United Kingdom.
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2157-21.2022
PubMed 
36717232
Published By 
Society for Neuroscience
History 
  • Received October 26, 2021
  • Revision received November 13, 2022
  • Accepted November 16, 2022
  • First published January 30, 2023.
Copyright & Usage 
Copyright © 2023 Tolomeo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Serenella Tolomeo1,2,
  2. Alex Baldacchino3, and
  3. J. Douglas Steele4
  1. 1Institute of High Performance Computing, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore;
  2. 2Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;
  3. 3Division of Population and Behavioral Science, Medical School, University of St Andrews, United Kingdom;
  4. 4Division of Imaging Science and Technology, Medical School, University of Dundee, United Kingdom.
  1. Correspondence to:
    Serenella Tolomeo, Institute of High Performance Computing, Agency for Science, Technology and Research, 1 Fusionopolis Way, 16-16, Connexis, Singapore, 138632, Singapore, Email: Serenella_Tolomeo{at}ihpc.a-star.edu.sg

Author contributions

  1. ST and JDS conceived experiments. ST, AB and JDS collected and analyzed the data. ST wrote the manuscript with support from AB and JDS. All authors approved the manuscript.

Disclosures

  • The funding sources played no part in the design of the study, analyses and interpretation of the data, nor manuscript preparation. The authors have no competing financial interests. The authors declare no financial or other conflicts of interest with regard to this work.

  • This work was supported by Dundee University Medical School Grant Number AT27 to ST and JDS. Spectroscopy was supported by an unrestricted work in progress agreement with Siemens Healthcare AG. We thank Dr Kent Berridge for comments on an earlier version of this manuscript.

Funding

  • Dundee University Medical School Grant

    AT27

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Blunted Expected Reward Value Signals in Binge Alcohol Drinkers
Serenella Tolomeo, Alex Baldacchino, J. Douglas Steele
Journal of Neuroscience 30 January 2023, JN-RM-2157-21; DOI: 10.1523/JNEUROSCI.2157-21.2022

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Blunted Expected Reward Value Signals in Binge Alcohol Drinkers
Serenella Tolomeo, Alex Baldacchino, J. Douglas Steele
Journal of Neuroscience 30 January 2023, JN-RM-2157-21; DOI: 10.1523/JNEUROSCI.2157-21.2022
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