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Research Articles, Cellular/Molecular

Leptin activates dopamine and GABA neurons in the substantia nigra via a local pars compacta-pars reticulata circuit

Maria Mancini, Takuya Hikima, Paul Witkovsky, Jyoti C. Patel, Dominic W. Stone, Alison H. Affinati and Margaret E. Rice
Journal of Neuroscience 24 March 2025, e1539242025; https://doi.org/10.1523/JNEUROSCI.1539-24.2025
Maria Mancini
1Department of Neuroscience and Physiology, NYU School of Medicine, New York, NY, USA
2Neuroscience Institute, NYU School of Medicine, New York, NY, USA
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Takuya Hikima
3Department of Neurosurgery, NYU School of Medicine, New York, NY, USA
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Paul Witkovsky
3Department of Neurosurgery, NYU School of Medicine, New York, NY, USA
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Jyoti C. Patel
2Neuroscience Institute, NYU School of Medicine, New York, NY, USA
3Department of Neurosurgery, NYU School of Medicine, New York, NY, USA
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Dominic W. Stone
3Department of Neurosurgery, NYU School of Medicine, New York, NY, USA
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Alison H. Affinati
4Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
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Margaret E. Rice
1Department of Neuroscience and Physiology, NYU School of Medicine, New York, NY, USA
2Neuroscience Institute, NYU School of Medicine, New York, NY, USA
3Department of Neurosurgery, NYU School of Medicine, New York, NY, USA
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  • For correspondence: margaret.rice@nyu.edu
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Leptin activates dopamine and GABA neurons in the substantia nigra via a local pars compacta-pars reticulata circuit
Maria Mancini, Takuya Hikima, Paul Witkovsky, Jyoti C. Patel, Dominic W. Stone, Alison H. Affinati, Margaret E. Rice
Journal of Neuroscience 24 March 2025, e1539242025; DOI: 10.1523/JNEUROSCI.1539-24.2025

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Leptin activates dopamine and GABA neurons in the substantia nigra via a local pars compacta-pars reticulata circuit
Maria Mancini, Takuya Hikima, Paul Witkovsky, Jyoti C. Patel, Dominic W. Stone, Alison H. Affinati, Margaret E. Rice
Journal of Neuroscience 24 March 2025, e1539242025; DOI: 10.1523/JNEUROSCI.1539-24.2025
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