PT  - JOURNAL ARTICLE
AU  - L Peichl
AU  - J Gonzalez-Soriano
TI  - Unexpected presence of neurofilaments in axon-bearing horizontal cells of the mammalian retina
AID  - 10.1523/JNEUROSCI.13-09-04091.1993
DP  - 1993 Sep 01
TA  - The Journal of Neuroscience
PG  - 4091--4100
VI  - 13
IP  - 9
4099  - http://www.jneurosci.org/content/13/9/4091.short
4100  - http://www.jneurosci.org/content/13/9/4091.full
SO  - J. Neurosci.1993 Sep 01; 13
AB  - In several mammals only one of the two types of retinal horizontal cell, the axonless A-type, appears to express neurofilaments. Neurofilament immunostaining of rodent retinas reveals a horizontal cell plexus that has previously been interpreted as belonging to A-type cells. Our intracellular Lucifer yellow injections strongly suggest that there are no A-type horizontal cells in rat and gerbil. Counterstaining of dye-injected cellular structures with a neurofilament antibody directly shows that the axon terminal systems of the axon-bearing B-type horizontal cells contain neurofilaments. These unexpected findings explain and reinterpret the neurofilament plexus in rodent retinas. In contrast, Lucifer yellow injections in guinea pig retina reveal both A- and B-type horizontal cells, showing that horizontal cell types are not uniform among rodents. In the guinea pig retina both A-type cells and B-type axon terminal systems contain neurofilaments.