RT Journal Article SR Electronic T1 Gases as biological messengers: nitric oxide and carbon monoxide in the brain JF The Journal of Neuroscience JO J. Neurosci. FD Society for Neuroscience SP 5147 OP 5159 DO 10.1523/JNEUROSCI.14-09-05147.1994 VO 14 IS 9 A1 Dawson, TM A1 Snyder, SH YR 1994 UL http://www.jneurosci.org/content/14/9/5147.abstract AB In a remarkably brief period of time, NO and CO have been recognized as putative neurotransmitters. These two novel messenger molecules have greatly expanded the criteria for candidacy of a chemical for the status of neurotransmitter and our notions about how synaptic transmission takes place. The involvement of NO and CO in several important aspects of neuronal function suggests that agents affecting the synthesis, transactions, and disposition of these gases are bound to have clinical relevance.