RT Journal Article
SR Electronic
T1 Tissue-specific expression of a Drosophila calcium-activated potassium channel
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 6250
OP 6259
DO 10.1523/JNEUROSCI.15-09-06250.1995
VO 15
IS 9
A1 Becker, MN
A1 Brenner, R
A1 Atkinson, NS
YR 1995
UL http://www.jneurosci.org/content/15/9/6250.abstract
AB The Drosophila slowpoke (slo) gene encodes a subunit of a CAK channel homologous to the vertebrate BK channel. We have examined slo expression throughout development. It is expressed in muscle cells, neurons of the CNS and PNS, mushroom bodies, a limited number of cells in embryonic and larval midgut and in epithelial-derived tracheal cells. The promoter has been cloned and shown to direct expression in the same pattern as the endogenous gene in both neural and epithelial- derived cells. During pupariation and embryogenesis, slo is expressed in muscles many hours prior to the appearance of functional channels.